Phenylpiperazine
1-Phenylpiperazine is a simple chemical compound featuring a phenyl group bound to a piperazine ring. The suffix ‘-piprazole’ is sometimes used in the names of drugs to indicate they belong to this class.[1]
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| Names | |
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| IUPAC name
1-phenylpiperazine | |
| Identifiers | |
3D model (JSmol) |
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| ChEMBL | |
| ChemSpider | |
| ECHA InfoCard | 100.001.969 |
PubChem CID |
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| UNII | |
CompTox Dashboard (EPA) |
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| Properties | |
| C10H14N2 | |
| Molar mass | 162.23 g/mol |
| Appearance | clear colourless to yellow liquid |
| Density | 1.028g/cm3 |
| Melting point | 18.8 °C (65.8 °F; 291.9 K) |
| Boiling point | 287.2 °C (549.0 °F; 560.3 K) at 760mmHg |
| insoluble | |
| Hazards | |
| Flash point | 138.3 °C (280.9 °F; 411.4 K) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
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| Infobox references | |
A number of phenylpiperazine derivatives are drugs, including:
Pharmaceuticals:
- Antrafenine — anti-inflammatory
- Aripiprazole — antipsychotic
- Bifeprunox — antipsychotic
- Brexpiprazole — antipsychotic
- Cariprazine — antipsychotic
- Ciprofloxacin — antibiotic
- Dapiprazole — alpha blocker
- Dropropizine — antitussive
- Elopiprazole — antipsychotic
- Etoperidone — antidepressant
- Itraconazole — antifungal
- Ketoconazole — antifungal
- Levodropropizine — antitussive
- Mepiprazole — anxiolytic
- Mianserin — antidepressant
- Naftopidil — antihypertensive
- Nefazodone — antidepressant
- Niaprazine — hypnotic
- Oxypertine — antipsychotic
- Posaconazole — antifungal
- Tioperidone — antipsychotic
- Tolpiprazole (Tranquilliser)
- Trazodone — antidepressant
- Umespirone — antipsychotic
- Urapidil — antihypertensive
- Vesnarinone — cardiotonic
Research chemicals:
- Acaprazine — anxiolytic
- Batoprazine — serenic (antiaggressive)
- Bifeprunox — antipsychotic
- BRL-15,572 — serotonergic
- CSP-2503 — anxiolytic
- DMPP — nicotinic
- EGIS-12,233 — serotonergic
- Elopiprazole — antipsychotic
- Eltoprazine — serenic
- Enciprazine — anxiolytic
- Enpiprazole — anxiolytic
- Ensaculin — nootropic
- Flibanserin — aphrodisiac
- Fluprazine — serenic
- Flesinoxan — antidepressant
- Lorpiprazole — anxiolytic
- Naluzotan — antidepressant
- Naphthylpiperazine — serotonergic
- Pardoprunox — antiparkinsonian
- S-14,506 — serotonergic
- S-14,671 — serotonergic
- S-15,535 — serotonergic
- SB-258,585 — serotonergic
- SB-271,046 — serotonergic
- SB-357,134 — serotonergic
- SB-399,885 — serotonergic
- Sonepiprazole — dopaminergic
- Tolpiprazole — anxiolytic
- Vilazodone — antidepressant
- Vortioxetine — antidepressant
- WAY-100,135 — serotonergic
- WAY-100,635 — serotonergic
- Zolertine — antihypertensive
Designer drugs:
See also
References
- World Health Organization (WHO) (2006). "The use of stems in the selection of International Nonproprietary Names (INN) for pharmaceutical substances" (PDF). Retrieved 27 April 2010.
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