MRGPRX1

MRGPRX1
Identifiers
Aliases	MRGPRX1, GPCR, MGRG2, MRGX1, SNSR4, MAS related GPR family member X1
External IDs	OMIM: 607227 MGI: 2441674 HomoloGene: 86246 GeneCards: MRGPRX1
Gene location (Human)
Chr.	Chromosome 11 (human)[1]
End	18,939,507 bp[1]
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)[2]
End	48,558,086 bp[2]
Gene ontology
Molecular function	• signal transducer activity; • G-protein coupled receptor activity; • transmembrane signaling receptor activity;
Cellular component	• cell membrane; • membrane; • integral component of membrane; • integral component of plasma membrane; • cell surface;
Biological process	• acute-phase response; • G-protein coupled receptor signaling pathway; • signal transduction; • cell surface receptor signaling pathway; • response to chloroquine;
	Sources:Amigo / QuickGO
Orthologs
	259249
	243979
	ENSG00000170255
	ENSMUSG00000050425
	Q96LB2
	Q3KNA1
	NM_147199
	NM_175531
	NP_671732
	NP_780740
	Wikidata
View/Edit Human	View/Edit Mouse

Mas-related G-protein coupled receptor member X1 is a protein that in humans is encoded by the MRGPRX1 gene.[5][6]

References

GRCh38: Ensembl release 89: ENSG00000170255 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000050425 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Dong X, Han S, Zylka MJ, Simon MI, Anderson DJ (Sep 2001). "A diverse family of GPCRs expressed in specific subsets of nociceptive sensory neurons". Cell. 106 (5): 619–32. doi:10.1016/S0092-8674(01)00483-4. PMID 11551509.
"Entrez Gene: MRGPRX1 MAS-related GPR, member X1".

Lembo PM, Grazzini E, Groblewski T, et al. (2002). "Proenkephalin A gene products activate a new family of sensory neuron--specific GPCRs". Nat. Neurosci. 5 (3): 201–9. doi:10.1038/nn815. PMID 11850634.
Takeda S, Kadowaki S, Haga T, et al. (2002). "Identification of G protein-coupled receptor genes from the human genome sequence". FEBS Lett. 520 (1–3): 97–101. doi:10.1016/S0014-5793(02)02775-8. PMID 12044878.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Galés C, Rebois RV, Hogue M, et al. (2005). "Real-time monitoring of receptor and G-protein interactions in living cells". Nat. Methods. 2 (3): 177–84. doi:10.1038/nmeth743. PMID 15782186.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.