TAS2R20

TAS2R20
Identifiers
Aliases	TAS2R20, T2R20, T2R49, T2R56, TAS2R49, taste 2 receptor member 20
External IDs	OMIM: 613962 HomoloGene: 107105 GeneCards: TAS2R20
Gene location (Human)
Chr.	Chromosome 12 (human)[1]
End	10,997,875 bp[1]
Gene ontology
Molecular function	• G-protein coupled receptor activity; • signal transducer activity; • bitter taste receptor activity;
Cellular component	• cell membrane; • membrane; • integral component of membrane;
Biological process	• sensory perception of taste; • signal transduction; • response to stimulus; • detection of chemical stimulus involved in sensory perception of bitter taste; • G-protein coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	259295
	n/a
	ENSG00000282612; ENSG00000255837; ENSG00000273092
	n/a
	P59543
	n/a
	NM_176889
	n/a
	NP_795370
	n/a
	Wikidata
View/Edit Human

Taste receptor type 2 member 20 is a protein that in humans is encoded by the TAS2R20 gene.[3]

References

Margolskee RF (2002). "Molecular mechanisms of bitter and sweet taste transduction". J. Biol. Chem. 277 (1): 1–4. doi:10.1074/jbc.R100054200. PMID 11696554.
Montmayeur JP, Matsunami H (2002). "Receptors for bitter and sweet taste". Curr. Opin. Neurobiol. 12 (4): 366–71. doi:10.1016/S0959-4388(02)00345-8. PMID 12139982.
Bufe B, Hofmann T, Krautwurst D, Raguse JD, Meyerhof W (2002). "The human TAS2R16 receptor mediates bitter taste in response to beta-glucopyranosides". Nat. Genet. 32 (3): 397–401. doi:10.1038/ng1014. PMID 12379855.
Zhang Y, Hoon MA, Chandrashekar J, Mueller KL, Cook B, Wu D, Zuker CS, Ryba NJ (2003). "Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways". Cell. 112 (3): 293–301. doi:10.1016/S0092-8674(03)00071-0. PMID 12581520.
Conte C, Ebeling M, Marcuz A, Nef P, Andres-Barquin PJ (2003). "Identification and characterization of human taste receptor genes belonging to the TAS2R family". Cytogenet. Genome Res. 98 (1): 45–53. doi:10.1159/000068546. PMID 12584440.
Fischer A, Gilad Y, Man O, Pääbo S (2005). "Evolution of bitter taste receptors in humans and apes". Mol. Biol. Evol. 22 (3): 432–6. doi:10.1093/molbev/msi027. PMID 15496549.
Go Y, Satta Y, Takenaka O, Takahata N (2006). "Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates". Genetics. 170 (1): 313–26. doi:10.1534/genetics.104.037523. PMC 1449719. PMID 15744053.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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