Galanolactone

Galanolactone is a diterpenoid lactone first isolated from ginger. It is known to be present in acetone extracts of ginger, and appears to be an antagonist at 5-HT3 receptors.[1]

Galanolactone
Names
IUPAC name
(3E)-3-[2-[(1R,2S)-5,5,8a-trimethylspiro[3,4,4a,6,7,8-hexahydro- 1H-naphthalene-2,2'-oxirane]-1-yl]ethylidene]oxolan-2-one
Identifiers
3D model (JSmol)
ChemSpider
MeSH galanolactone
Properties
C20H30O3
Molar mass 318.45 g/mol
Solubility in acetone Soluble
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

References

  1. Huang, Q.; Iwamoto, Y.; Aoki, S.; Tanaka, N.; Tajima, K.; Yamahara, J.; Takaishi, Y.; Yoshida, M.; Tomimatsu, T.; Tamai, Y. (1991). "Anti-5-hydroxytryptamine3 effect of galanolactone, diterpenoid isolated from ginger". Chemical & Pharmaceutical Bulletin. 39 (2): 397–399. doi:10.1248/cpb.39.397. PMID 2054863.
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