TAS2R39

TAS2R39
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2GFZ
Identifiers
Aliases	TAS2R39, T2R39, T2R57, taste 2 receptor member 39
External IDs	MGI: 2681308 HomoloGene: 52214 GeneCards: TAS2R39
Gene location (Human)
Chr.	Chromosome 7 (human)[1]
End	143,184,435 bp[1]
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)[2]
End	42,141,895 bp[2]
Gene ontology
Molecular function	• G-protein coupled receptor activity; • signal transducer activity; • bitter taste receptor activity;
Cellular component	• cell membrane; • membrane; • integral component of membrane;
Biological process	• detection of chemical stimulus involved in sensory perception of bitter taste; • signal transduction; • response to stimulus; • sensory perception of taste; • G-protein coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	259285
	353148
	ENSG00000236398
	ENSMUSG00000047102
	P59534
	Q7TQA5
	NM_176881
	NM_181275
	NP_795362
	NP_851792
	Wikidata
View/Edit Human	View/Edit Mouse

Taste receptor type 2 member 39 is a protein that in humans is encoded by the TAS2R39 gene.[5][6]

References

GRCh38: Ensembl release 89: ENSG00000236398 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000047102 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Bufe B, Hofmann T, Krautwurst D, Raguse JD, Meyerhof W (Oct 2002). "The human TAS2R16 receptor mediates bitter taste in response to beta-glucopyranosides". Nat Genet. 32 (3): 397–401. doi:10.1038/ng1014. PMID 12379855.
"Entrez Gene: TAS2R39 taste receptor, type 2, member 39".

Margolskee RF (2002). "Molecular mechanisms of bitter and sweet taste transduction". J. Biol. Chem. 277 (1): 1–4. doi:10.1074/jbc.R100054200. PMID 11696554.
Montmayeur JP, Matsunami H (2002). "Receptors for bitter and sweet taste". Curr. Opin. Neurobiol. 12 (4): 366–71. doi:10.1016/S0959-4388(02)00345-8. PMID 12139982.
Zhang Y, Hoon MA, Chandrashekar J, Mueller KL, Cook B, Wu D, Zuker CS, Ryba NJ (2003). "Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways". Cell. 112 (3): 293–301. doi:10.1016/S0092-8674(03)00071-0. PMID 12581520.
Fischer A, Gilad Y, Man O, Pääbo S (2005). "Evolution of bitter taste receptors in humans and apes". Mol. Biol. Evol. 22 (3): 432–6. doi:10.1093/molbev/msi027. PMID 15496549.
Go Y, Satta Y, Takenaka O, Takahata N (2006). "Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates". Genetics. 170 (1): 313–26. doi:10.1534/genetics.104.037523. PMC 1449719. PMID 15744053.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.