GPR78

GPR78
Identifiers
Aliases	GPR78, G protein-coupled receptor 78
External IDs	OMIM: 606921 HomoloGene: 50960 GeneCards: GPR78
Gene location (Human)
Chr.	Chromosome 4 (human)[1]
End	8,619,761 bp[1]
Gene ontology
Molecular function	• G-protein coupled receptor activity; • signal transducer activity; • GO:0001948 protein binding;
Cellular component	• integral component of membrane; • cell membrane; • membrane; • intracellular;
Biological process	• G-protein coupled receptor signaling pathway; • adenylate cyclase-activating G-protein coupled receptor signaling pathway; • signal transduction;
	Sources:Amigo / QuickGO
Orthologs
	27201
	n/a
	ENSG00000155269
	n/a
	Q96P69
	n/a
	NM_080819
	n/a
	NP_543009
	n/a
	Wikidata
View/Edit Human

Probable G-protein coupled receptor 78 is a protein that in humans is encoded by the GPR78 gene.[3][4]

G protein-coupled receptors (GPCRs, or GPRs) contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins.[supplied by OMIM][4]

References

GRCh38: Ensembl release 89: ENSG00000155269 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Lee DK, Nguyen T, Lynch KR, Cheng R, Vanti WB, Arkhitko O, Lewis T, Evans JF, George SR, O'Dowd BF (Sep 2001). "Discovery and mapping of ten novel G protein-coupled receptor genes". Gene. 275 (1): 83–91. doi:10.1016/S0378-1119(01)00651-5. PMID 11574155.
"Entrez Gene: GPR78 G protein-coupled receptor 78".

van Laar T, Schouten T, Hoogervorst E, et al. (2000). "The novel MMS-inducible gene Mif1/KIAA0025 is a target of the unfolded protein response pathway". FEBS Lett. 469 (1): 123–31. doi:10.1016/S0014-5793(00)01253-9. PMID 10708769.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Clark HF, Gurney AL, Abaya E, et al. (2003). "The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Underwood SL, Christoforou A, Thomson PA, et al. (2006). "Association analysis of the chromosome 4p-located G protein-coupled receptor 78 (GPR78) gene in bipolar affective disorder and schizophrenia". Mol. Psychiatry. 11 (4): 384–94. doi:10.1038/sj.mp.4001786. PMID 16389273.

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[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000155269 - Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11574155-3] Lee DK, Nguyen T, Lynch KR, Cheng R, Vanti WB, Arkhitko O, Lewis T, Evans JF, George SR, O'Dowd BF (Sep 2001). "Discovery and mapping of ten novel G protein-coupled receptor genes". Gene. 275 (1): 83–91. doi:10.1016/S0378-1119(01)00651-5. PMID 11574155.

[entrez-4] "Entrez Gene: GPR78 G protein-coupled receptor 78".

GPR78

References

Further reading