BRL-44408

BRL-44408 is a drug used in scientific research which acts as a selective antagonist for the α2A adrenoreceptor.[1] It has been suggested as having potential therapeutic application in the treatment of extrapyramidal side effects produced by some antipsychotic medications.[2]

BRL-44408
Identifiers
CAS Number
PubChem CID
IUPHAR/BPS
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC13H17N3
Molar mass215.300 g·mol−1
3D model (JSmol)
 NY (what is this?)  (verify)

References

  1. Alberts P (January 1993). "Subtype classification of presynaptic alpha 2-adrenoceptors". General Pharmacology. 24 (1): 1–8. doi:10.1016/0306-3623(93)90003-g. PMID 8387042.
  2. Imaki J, Mae Y, Shimizu S, Ohno Y (April 2009). "Therapeutic potential of alpha2 adrenoceptor antagonism for antipsychotic-induced extrapyramidal motor disorders". Neuroscience Letters. 454 (2): 143–7. doi:10.1016/j.neulet.2009.03.001. PMID 19429072.
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