SB-200646

SB-200646 is a 5-HT2 receptor antagonist with anxiolytic properties in rats. It was the first 5-HT2 antagonist discovered to have selectivity of 5-HT2C/2B over 5-HT2A.[1]

SB-200646
Clinical data
ATC code
  • none
Legal status
Legal status
  • UN: Unscheduled
Identifiers
PubChem CID
ChemSpider
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC15H14N4O
Molar mass266.304 g·mol−1
3D model (JSmol)

References

  1. Kennett GA, Wood MD, Glen A, Grewal S, Forbes I, Gadre A, Blackburn TP (March 1994). "In vivo properties of SB 200646A, a 5-HT2C/2B receptor antagonist". British Journal of Pharmacology. 111 (3): 797–802. doi:10.1111/j.1476-5381.1994.tb14808.x. PMC 1910094. PMID 7912626.
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