I-SMAD
I-SMAD or Inhibitor SMAD is a subclass of SMADs that are involved in the modulation of transforming growth factor beta ligands. This class includes SMAD6 and SMAD7. They compete with SMAD4 and consequently regulate the transcription of its gene products.
See also
External links
- I-Smad+Proteins at the US National Library of Medicine Medical Subject Headings (MeSH)
Cell signaling: TGFβ signaling pathway | |||||||
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| TGF beta superfamily of ligands |
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| TGF beta receptors (Activin, BMP, family) |
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| Transducers/SMAD | |||||||
| Ligand inhibitors | |||||||
| Coreceptors | |||||||
| Other | |||||||
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see also transcription factor/coregulator deficiencies | |||||||||||||||||||||||||||||||
TGFβ receptor superfamily modulators | |||||||||||||||
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| Type I |
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| Type II |
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| Type III |
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| Unsorted |
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