CEBPG

CCAAT/enhancer-binding protein gamma is a protein that in humans is encoded by the CEBPG gene.[5][6]

CEBPG
Identifiers
Aliases	CEBPG, GPE1BP, IG/EBP-1, CCAAT/enhancer binding protein gamma, CCAAT enhancer binding protein gamma
External IDs	OMIM: 138972 MGI: 104982 HomoloGene: 1368 GeneCards: CEBPG
Gene location (Human) Chr. Chromosome 19 (human)[1] Band 19q13.11 Start 33,373,685 bp[1] End 33,382,686 bp[1]
Gene location (Mouse) Chr. Chromosome 7 (mouse)[2] Band 7|7 B2 Start 35,046,422 bp[2] End 35,056,573 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • DNA binding • protein homodimerization activity • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity • GO:0001077, GO:0001212, GO:0001213, GO:0001211, GO:0001205 DNA-binding transcription activator activity, RNA polymerase II-specific • transcription factor binding • GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding • GO:0001948 protein binding • sequence-specific DNA binding • protein heterodimerization activity • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific • double-stranded DNA binding • RNA polymerase II core promoter proximal region sequence-specific DNA binding, bending Cellular component • nucleoplasm • cell nucleus Biological process • regulation of transcription, DNA-templated • positive regulation of interferon-gamma biosynthetic process • positive regulation of DNA repair • positive regulation of sequence-specific DNA binding transcription factor activity • negative regulation of sequence-specific DNA binding transcription factor activity • transcription, DNA-templated • enucleate erythrocyte differentiation • immune response • mRNA metabolic process • B cell differentiation • positive regulation of DNA binding • positive regulation of transcription from RNA polymerase II promoter • natural killer cell mediated cytotoxicity • transcription from RNA polymerase II promoter • liver development • regulation of transcription from RNA polymerase II promoter Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	1054	12611
Ensembl	ENSG00000153879	ENSMUSG00000056216
UniProt	P53567	P53568
RefSeq (mRNA)	NM_001806 NM_001252296	NM_009884
RefSeq (protein)	NP_001239225 NP_001797	NP_034014
Location (UCSC)	Chr 19: 33.37 – 33.38 Mb	Chr 7: 35.05 – 35.06 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

The C/EBP family of transcription factors regulates viral and cellular CCAAT/enhancer element-mediated transcription. C/EBP proteins contain the bZIP region, which is characterized by two motifs in the C-terminal half of the protein: a basic region involved in DNA binding and a leucine zipper motif involved in dimerization. The C/EBP family consist of several related proteins, C/EBP alpha, C/EBP beta, C/EBP gamma, and C/EBP delta, that form homodimers and that form heterodimers with each other. CCAAT/enhancer binding protein gamma may cooperate with Fos to bind PRE-I enhancer elements.[6]