Estradiol/megestrol acetate

Estradiol /
megestrol acetate
Estradiol (top) and
megestrol acetate (bottom)
Combination of
Estradiol Estrogen
Megestrol acetate Progestogen
Clinical data
Trade names Mego-E, Chinese injectable No. 2
Synonyms E2/MGA
Routes of
administration		 Intramuscular injection

Estradiol/megestrol acetate (E2/MGA), sold under the brand names Mego-E and Chinese injectable No. 2, is a form of combined injectable birth control which is used in the People's Republic of China.[1][2][3][4] It contains 3.5 mg estradiol (E2), an estrogen, and 25 mg megestrol acetate (MGA), a progestin.[1][2][3] It is a microcrystalline aqueous suspension with a defined particle size range.[1][2][3] The medication is given once per month by injection into muscle.[1][2][3]

See also

References

  1. 1 2 3 4 Garza-Flores J (April 1994). "Pharmacokinetics of once-a-month injectable contraceptives". Contraception. 49 (4): 347–59. doi:10.1016/0010-7824(94)90032-9. PMID 8013219.
  2. 1 2 3 4 Sang GW (April 1994). "Pharmacodynamic effects of once-a-month combined injectable contraceptives". Contraception. 49 (4): 361–85. doi:10.1016/0010-7824(94)90033-7. PMID 8013220.
  3. 1 2 3 4 Bagade O, Pawar V, Patel R, Patel B, Awasarkar V, Diwate S (2014). "Increasing use of long-acting reversible contraception: safe, reliable, and cost-effective birth control" (PDF). World J Pharm Pharm Sci. 3 (10): 364–392. ISSN 2278-4357.
  4. ↑ IARC Working Group on the Evaluation of Carcinogenic Risks to Humans; International Agency for Research on Cancer (1 January 1999). Hormonal Contraception and Post-menopausal Hormonal Therapy (PDF). IARC. p. 65. ISBN 978-92-832-1272-0. ; Hormonal Contraception and Post-menopausal Hormonal Therapy at Google Books


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