Estradiol benzoate/progesterone
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Combination of |
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Estradiol benzoate |
Estrogen |
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Progesterone |
Progestogen |
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Clinical data |
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Trade names |
Di Pro Oleosum, Duogynon, Duoton Fort T P, Emmenovis, Gestrygen, Lutofolone, Menovis, Mestrolar, Metrigen Fuerte, Nomestrol, Phenokinon-F, Pro-Estramon-S, Prodiol, Proger F, Progestediol[1][2] |
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Synonyms |
EB/P4 |
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Routes of administration |
Intramuscular injection |
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ATC code |
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Identifiers |
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CAS Number |
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PubChem CID |
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Estradiol benzoate/progesterone (EB/P4) is a combination medication formulation of estradiol benzoate, an estrogen, and progesterone, a progestogen, which is used via intramuscular injection.[1][2][3] It has been marketed under a variety of brand names including Component E-S, Component EC, Di Pro Oleosum, Duogynon, Duogynon ampule, Duogynon forte, Duogynon simplex, Duoton Fort T P, Emmenovis, Estroprogyn, Gestrygen, Implus-C, Implus S, Jephagynon, Klimovan, Limovanil, Lutofolone, Menovis, Menstrogen Forte, Mestrolar, Metrigen Fuerte, Nomestrol, Phenokinon-F, Pro-Estramon-S, Prodiol, Proger F, Progestediol, Sistocyclin, Synovex C, and Tonevex S.[1][2][3][4] The medication is available in various countries including Latin American countries, Egypt, Italy, Lebanon, Taiwan, Thailand, Turkey, Malaysia, and Ethiopia.[1][2][3]
Under the brand name Vermagest, EB/P4 (30 mg / 30 mg ampoule) is also used as an injectable form of emergency contraception within 48 hours of sexual intercourse in El Salvador, Honduras, and Nicaragua.[5][6][7]