Relaxin/insulin-like family peptide receptor 3

RXFP3
Identifiers
AliasesRXFP3, GPCR135, RLN3R1, RXFPR3, SALPR, Relaxin/insulin-like family peptide receptor 3, relaxin/insulin like family peptide receptor 3, relaxin family peptide receptor 3
External IDsMGI: 2441827 HomoloGene: 9568 GeneCards: RXFP3
Gene location (Human)
Chr.Chromosome 5 (human)[1]
Band5p13.2Start33,936,386 bp[1]
End33,938,237 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

51289

239336

Ensembl

ENSG00000182631
ENSG00000277069

ENSMUSG00000060735

UniProt

Q9NSD7

Q8BGE9

RefSeq (mRNA)

NM_016568

NM_178717

RefSeq (protein)

NP_057652

NP_848832

Location (UCSC)Chr 5: 33.94 – 33.94 MbChr 15: 11.03 – 11.04 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Relaxin/insulin-like family peptide receptor 3, also known as RXFP3, is a human G-protein coupled receptor.[5]

See also

References

  1. 1 2 3 ENSG00000277069 GRCh38: Ensembl release 89: ENSG00000182631, ENSG00000277069 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000060735 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. ↑ "Entrez Gene: RXFP3 relaxin/insulin-like family peptide receptor 3".
  • "Relaxin Family Peptide Receptors: RXFP3". IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology.

Further reading

  • Bathgate RA, Ivell R, Sanborn BM, et al. (2005). "Receptors for relaxin family peptides". Ann. N. Y. Acad. Sci. 1041: 61–76. doi:10.1196/annals.1282.010. PMID 15956688.
  • Bathgate RA, Ivell R, Sanborn BM, et al. (2006). "International Union of Pharmacology LVII: recommendations for the nomenclature of receptors for relaxin family peptides". Pharmacol. Rev. 58 (1): 7–31. doi:10.1124/pr.58.1.9. PMID 16507880.
  • Matsumoto M, Kamohara M, Sugimoto T, et al. (2000). "The novel G-protein coupled receptor SALPR shares sequence similarity with somatostatin and angiotensin receptors". Gene. 248 (1–2): 183–9. doi:10.1016/S0378-1119(00)00123-2. PMID 10806363.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Liu C, Eriste E, Sutton S, et al. (2004). "Identification of relaxin-3/INSL7 as an endogenous ligand for the orphan G-protein-coupled receptor GPCR135". J. Biol. Chem. 278 (50): 50754–64. doi:10.1074/jbc.M308995200. PMID 14522968.
  • Liu C, Chen J, Kuei C, et al. (2005). "Relaxin-3/insulin-like peptide 5 chimeric peptide, a selective ligand for G protein-coupled receptor (GPCR)135 and GPCR142 over leucine-rich repeat-containing G protein-coupled receptor 7". Mol. Pharmacol. 67 (1): 231–40. doi:10.1124/mol.104.006700. PMID 15465925.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Van der Westhuizen ET, Sexton PM, Bathgate RA, Summers RJ (2005). "Responses of GPCR135 to human gene 3 (H3) relaxin in CHO-K1 cells determined by microphysiometry". Ann. N. Y. Acad. Sci. 1041: 332–7. doi:10.1196/annals.1282.053. PMID 15956730.

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