ELTD1

ADGRL4
Identifiers
AliasesADGRL4, ETL, KPG_003, ELTD1, adhesion G protein-coupled receptor L4
External IDsMGI: 2655562 HomoloGene: 11170 GeneCards: ADGRL4
Gene location (Human)
Chr.Chromosome 1 (human)[1]
Band1p31.1Start78,889,764 bp[1]
End79,006,718 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

64123

170757

Ensembl

ENSG00000162618

ENSMUSG00000039167

UniProt

Q9HBW9

Q923X1

RefSeq (mRNA)

NM_022159

NM_133222

RefSeq (protein)

NP_071442

NP_573485

Location (UCSC)Chr 1: 78.89 – 79.01 MbChr 3: 151.44 – 151.55 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

EGF, latrophilin and seven transmembrane domain-containing protein 1 is a latrophilin-like orphan receptor of the adhesion G protein-coupled receptor family. In humans this protein is encoded by the ELTD1 gene.[5][6] ELTD1 appears to have a role in angiogenesis, both physiological and pathological, as well as glioblastoma.[7]

See also

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000162618 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000039167 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. ↑ Nechiporuk T, Urness LD, Keating MT (May 2001). "ETL, a novel seven-transmembrane receptor that is developmentally regulated in the heart. ETL is a member of the secretin family and belongs to the epidermal growth factor-seven-transmembrane subfamily". J Biol Chem. 276 (6): 4150–4157. doi:10.1074/jbc.M004814200. PMID 11050079.
  6. ↑ "Entrez Gene: ELTD1 EGF, latrophilin and seven transmembrane domain containing 1".
  7. ↑ Dricu, Anica; Serban, Florentina; Artene, Stefan-Alexandru; Georgescu, Ada Maria; Purcaru, Stefana Oana; Tache, Daniela Elise; Alexandru, Oana (December 2015). "Epidermal growth factor, latrophilin, and seven transmembrane domain-containing protein 1 marker, a novel angiogenesis marker". OncoTargets and Therapy: 3767. doi:10.2147/OTT.S93843.

Further reading

  • Venter JC, Adams MD, Myers EW, et al. (2001). "The sequence of the human genome". Science. 291 (5507): 1304–1351. doi:10.1126/science.1058040. PMID 11181995.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–16903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–2270. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
  • Bjarnadóttir TK, Fredriksson R, Höglund PJ, et al. (2005). "The human and mouse repertoire of the adhesion family of G-protein-coupled receptors". Genomics. 84 (1): 23–33. doi:10.1016/j.ygeno.2003.12.004. PMID 15203201.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–2127. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Liu T, Qian WJ, Gritsenko MA, et al. (2006). "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry". J. Proteome Res. 4 (6): 2070–2080. doi:10.1021/pr0502065. PMC 1850943. PMID 16335952.
  • Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.


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