GPR78

GPR78
Identifiers
AliasesGPR78, G protein-coupled receptor 78
External IDsHomoloGene: 50960 GeneCards: GPR78
Gene location (Human)
Chr.Chromosome 4 (human)[1]
Band4p16.1Start8,558,725 bp[1]
End8,619,761 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

27201

n/a

Ensembl

ENSG00000155269

n/a

UniProt

Q96P69

n/a

RefSeq (mRNA)

NM_080819

n/a

RefSeq (protein)

NP_543009

n/a

Location (UCSC)Chr 4: 8.56 – 8.62 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

Probable G-protein coupled receptor 78 is a protein that in humans is encoded by the GPR78 gene.[3][4]

G protein-coupled receptors (GPCRs, or GPRs) contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins.[supplied by OMIM][4]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000155269 - Ensembl, May 2017
  2. "Human PubMed Reference:".
  3. Lee DK, Nguyen T, Lynch KR, Cheng R, Vanti WB, Arkhitko O, Lewis T, Evans JF, George SR, O'Dowd BF (Sep 2001). "Discovery and mapping of ten novel G protein-coupled receptor genes". Gene. 275 (1): 83–91. doi:10.1016/S0378-1119(01)00651-5. PMID 11574155.
  4. 1 2 "Entrez Gene: GPR78 G protein-coupled receptor 78".

Further reading

  • van Laar T, Schouten T, Hoogervorst E, et al. (2000). "The novel MMS-inducible gene Mif1/KIAA0025 is a target of the unfolded protein response pathway". FEBS Lett. 469 (1): 123–31. doi:10.1016/S0014-5793(00)01253-9. PMID 10708769.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Clark HF, Gurney AL, Abaya E, et al. (2003). "The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Underwood SL, Christoforou A, Thomson PA, et al. (2006). "Association analysis of the chromosome 4p-located G protein-coupled receptor 78 (GPR78) gene in bipolar affective disorder and schizophrenia". Mol. Psychiatry. 11 (4): 384–94. doi:10.1038/sj.mp.4001786. PMID 16389273.
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