Galcanezumab
Monoclonal antibody | |
---|---|
Type | Whole antibody |
Source | Human |
Target | CALCA, CALCB |
Clinical data | |
Trade names | Emgality |
Synonyms | LY2951742 |
ATC code |
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Identifiers | |
CAS Number | |
ChemSpider |
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UNII | |
Chemical and physical data | |
Formula | C6392H9854N1686O2018S46 |
Molar mass | 144.1 kDa |
Galcanezumab, marketed under the trade name Emgality, is a humanized monoclonal antibody used for the prevention of migraine.[1][2] It is directed against calcitonin-related polypeptides alpha and beta.
This drug was developed by Eli Lilly & Co. As of July 2017.[3] The drug was approved by the US FDA in September 2018, becoming the third marketed CGRP inhibitor for the United States.[4]
See also
- Other anti-migraine antibodies blocking the CGRP pathway
References
- ↑ Statement On A Nonproprietary Name Adopted By The USAN Council - Galcanezumab, American Medical Association.
- ↑ World Health Organization (2015). "International Nonproprietary Names for Pharmaceutical Substances (INN). Proposed INN: List 114" (PDF). WHO Drug Information. 29 (4).
- ↑ H. Spreitzer (3 July 2017). "Neue Wirkstoffe: Galcanezumab, Fremanezumab und Eptinezumab". Österreichische Apothekerzeitung (in German) (14/2017).
- ↑ "US FDA approves Lilly migraine drug at a price that is the same as its rivals". CNBC. Reuters. 28 September 2018. Retrieved 29 September 2018.
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