GPR144

ADGRD2
Identifiers
AliasesADGRD2, PGR24, GPR144, adhesion G protein-coupled receptor D2
External IDsHomoloGene: 130029 GeneCards: ADGRD2
Gene location (Human)
Chr.Chromosome 9 (human)[1]
Band9q33.3Start124,451,425 bp[1]
End124,478,589 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

347088

n/a

Ensembl

ENSG00000180264

n/a

UniProt

n/a

n/a

RefSeq (mRNA)

NM_001161808
NM_182611

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)Chr 9: 124.45 – 124.48 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

Probable G-protein coupled receptor 144 is a protein that in humans is encoded by the GPR144 gene.[3][4] This gene encodes a member of the adhesion-GPCR family of receptors. Family members are characterised by an extended extracellular region with a variable number of protein domains coupled to a TM7 domain via a domain known as the GPCR-Autoproteolysis INducing (GAIN) domain.[5][6]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000180264 - Ensembl, May 2017
  2. ↑ "Human PubMed Reference:".
  3. ↑ "Entrez Gene: GPR144 G protein-coupled receptor 144".
  4. ↑ Fredriksson R, Lagerstrom MC, Hoglund PJ, Schioth HB (Nov 2002). "Novel human G protein-coupled receptors with long N-terminals containing GPS domains and Ser/Thr-rich regions". FEBS Lett. 531 (3): 407–14. doi:10.1016/S0014-5793(02)03574-3. PMID 12435584.
  5. ↑ Stacey M, Yona S (2011). AdhesionGPCRs: Structure to Function (Advances in Experimental Medicine and Biology). Berlin: Springer. ISBN 1-4419-7912-3.
  6. ↑ Araç D, Boucard AA, Bolliger MF, Nguyen J, Soltis SM, Südhof TC, Brunger AT (March 2012). "A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis". EMBO J. 31 (6): 1364–78. doi:10.1038/emboj.2012.26. PMC 3321182. PMID 22333914.

Further reading

  • Vassilatis DK, Hohmann JG, Zeng H, et al. (2003). "The G protein-coupled receptor repertoires of human and mouse". Proc. Natl. Acad. Sci. U.S.A. 100 (8): 4903–8. doi:10.1073/pnas.0230374100. PMC 153653. PMID 12679517.
  • Humphray SJ, Oliver K, Hunt AR, et al. (2004). "DNA sequence and analysis of human chromosome 9". Nature. 429 (6990): 369–74. doi:10.1038/nature02465. PMC 2734081. PMID 15164053.
  • Bjarnadóttir TK, Fredriksson R, Höglund PJ, et al. (2005). "The human and mouse repertoire of the adhesion family of G-protein-coupled receptors". Genomics. 84 (1): 23–33. doi:10.1016/j.ygeno.2003.12.004. PMID 15203201.
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