GPR61

GPR61
Identifiers
AliasesGPR61, BALGR, GPCR3, G protein-coupled receptor 61
External IDsMGI: 2441719 HomoloGene: 12910 GeneCards: GPR61
Gene location (Human)
Chr.Chromosome 1 (human)[1]
Band1p13.3Start109,539,872 bp[1]
End109,548,406 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

83873

229714

Ensembl

ENSG00000156097

ENSMUSG00000046793

UniProt

Q9BZJ8

Q8C010

RefSeq (mRNA)

NM_031936

NM_175470
NM_001305461

RefSeq (protein)

NP_114142

NP_001292390

Location (UCSC)Chr 1: 109.54 – 109.55 MbChr 3: 108.15 – 108.15 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Probable G-protein coupled receptor 61 is a protein that in humans is encoded by the GPR61 gene.[5][6][7]

This gene belongs to the G-protein coupled receptor 1 family. G protein-coupled receptors contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. The protein encoded by this gene is most closely related to biogenic amine receptors.[7]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000156097 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000046793 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. ↑ Lee DK, George SR, Cheng R, Nguyen T, Liu Y, Brown M, Lynch KR, O'Dowd BF (Feb 2001). "Identification of four novel human G protein-coupled receptors expressed in the brain". Brain Res Mol Brain Res. 86 (1–2): 13–22. doi:10.1016/S0169-328X(00)00242-4. PMID 11165367.
  6. ↑ Cikos S, Gregor P, Koppel J (Nov 2001). "Cloning of a novel biogenic amine receptor-like G protein-coupled receptor expressed in human brain". Biochim Biophys Acta. 1521 (1–3): 66–72. doi:10.1016/s0167-4781(01)00289-5. PMID 11690637.
  7. 1 2 "Entrez Gene: GPR61 G protein-coupled receptor 61".

Further reading

  • Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. doi:10.1038/nature04727. PMID 16710414.
  • Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
  • Conner AC, Hay DL, Simms J, et al. (2005). "A key role for transmembrane prolines in calcitonin receptor-like receptor agonist binding and signalling: implications for family B G-protein-coupled receptors". Mol. Pharmacol. 67 (1): 20–31. doi:10.1124/mol.67.1. PMID 15615699.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Takeda S, Kadowaki S, Haga T, et al. (2002). "Identification of G protein-coupled receptor genes from the human genome sequence". FEBS Lett. 520 (1–3): 97–101. doi:10.1016/S0014-5793(02)02775-8. PMID 12044878.

See also

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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