KCNT2

KCNT2
Identifiers
AliasesKCNT2, KCa4.2, SLICK, SLO2.1, potassium sodium-activated channel subfamily T member 2, EIEE57
External IDsMGI: 3036273 HomoloGene: 16121 GeneCards: KCNT2
Gene location (Human)
Chr.Chromosome 1 (human)[1]
Band1q31.3Start196,225,779 bp[1]
End196,609,225 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

343450

240776

Ensembl

ENSG00000162687

ENSMUSG00000052726

UniProt

Q6UVM3

n/a

RefSeq (mRNA)

NM_001287819
NM_001287820
NM_198503

NM_001081027

RefSeq (protein)

NP_001274748
NP_001274749
NP_940905

n/a

Location (UCSC)Chr 1: 196.23 – 196.61 MbChr 1: 140.25 – 140.61 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Potassium channel subfamily T, member 2, also known as KCNT2 is a human gene that encodes the KNa protein. KCNT2, also known as the Slick channel (sequence like an intermediate calcium channel) is an outwardly rectifying potassium channel activated by internal raises in sodium or chloride ions.

See also

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000162687 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000052726 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".

Further reading

  • Bhattacharjee A, Joiner WJ, Wu M, et al. (2003). "Slick (Slo2.1), a rapidly-gating sodium-activated potassium channel inhibited by ATP". J. Neurosci. 23 (37): 11681–91. PMID 14684870.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Santi CM, Ferreira G, Yang B, et al. (2006). "Opposite regulation of Slick and Slack K+ channels by neuromodulators". J. Neurosci. 26 (19): 5059–68. doi:10.1523/JNEUROSCI.3372-05.2006. PMID 16687497.
  • Wei AD, Gutman GA, Aldrich R, et al. (2005). "International Union of Pharmacology. LII. Nomenclature and molecular relationships of calcium-activated potassium channels". Pharmacol. Rev. 57 (4): 463–72. doi:10.1124/pr.57.4.9. PMID 16382103.


This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.