KCNG4

KCNG4
Identifiers
AliasesKCNG4, KV6.3, KV6.4, potassium voltage-gated channel modifier subfamily G member 4
External IDsMGI: 1913983 HomoloGene: 23553 GeneCards: KCNG4
Gene location (Human)
Chr.Chromosome 16 (human)[1]
Band16q24.1Start84,218,667 bp[1]
End84,239,750 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

93107

66733

Ensembl

ENSG00000168418

ENSMUSG00000045246

UniProt

Q8TDN1

Q80XM3

RefSeq (mRNA)

NM_172347
NM_133490

NM_025734
NM_001357210

RefSeq (protein)

NP_758857

NP_080010
NP_001344139

Location (UCSC)Chr 16: 84.22 – 84.24 MbChr 8: 119.62 – 119.64 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Potassium voltage-gated channel subfamily G member 4 is a protein that in humans is encoded by the KCNG4 gene.[5][5][6] The protein encoded by this gene is a voltage-gated potassium channel subunit.[6]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000168418 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000045246 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. 1 2 Ottschytsch N, Raes A, Van Hoorick D, Snyders DJ (Jun 2002). "Obligatory heterotetramerization of three previously uncharacterized Kv channel alpha-subunits identified in the human genome". Proc Natl Acad Sci U S A. 99 (12): 7986–91. doi:10.1073/pnas.122617999. PMC 123007. PMID 12060745.
  6. 1 2 Gutman GA, Chandy KG, Grissmer S, Lazdunski M, McKinnon D, Pardo LA, Robertson GA, Rudy B, Sanguinetti MC, Stuhmer W, Wang X (Dec 2005). "International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels". Pharmacol Rev. 57 (4): 473–508. doi:10.1124/pr.57.4.10. PMID 16382104.

Further reading

  • Mederos Y, Schnitzler M, Rinné S, Skrobek L, et al. (2009). "Mutation of histidine 105 in the T1 domain of the potassium channel Kv2.1 disrupts heteromerization with Kv6.3 and Kv6.4". J. Biol. Chem. 284 (7): 4695–704. doi:10.1074/jbc.M808786200. PMID 19074135.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Ottschytsch N, Raes AL, Timmermans JP, Snyders DJ (2005). "Domain analysis of Kv6.3, an electrically silent channel". J. Physiol. 568 (Pt 3): 737–47. doi:10.1113/jphysiol.2005.090142. PMC 1464172. PMID 16096342.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.


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