Cyclic nucleotide-gated channel alpha 4

CNGA4
Identifiers
AliasesCNGA4, CNCA2, CNG-4, CNG4, CNG5, CNGB2, OCNC2, OCNCBETA, OCNCb, Cyclic nucleotide-gated channel alpha 4, cyclic nucleotide gated channel alpha 4
External IDsMGI: 2664099 HomoloGene: 13579 GeneCards: CNGA4
Gene location (Human)
Chr.Chromosome 11 (human)[1]
Band11p15.4Start6,234,765 bp[1]
End6,244,429 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

1262

233649

Ensembl

ENSG00000132259

ENSMUSG00000030897

UniProt

Q8IV77

Q3UW12

RefSeq (mRNA)

NM_001037329

NM_001033317

RefSeq (protein)

NP_001032406

NP_001028489

Location (UCSC)Chr 11: 6.23 – 6.24 MbChr 7: 105.4 – 105.41 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Cyclic nucleotide-gated cation channel alpha-4 is a protein that in humans is encoded by the CNGA4 gene.[5][6][7]

CNGA4 is a modulatory subunit of vertebrate cyclic nucleotide-gated membrane channels that transduce odorant signals (Munger et al., 2001).[supplied by OMIM][7]

See also

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000132259 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000030897 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. ↑ Bradley J, Frings S, Yau KW, Reed R (Dec 2001). "Nomenclature for Ion channel Subunits". Science. 294 (5549): 2095–6. doi:10.1126/science.294.5549.2095. PMC 2901924. PMID 11764791.
  6. ↑ Hofmann F, Biel M, Kaupp UB (Dec 2005). "International Union of Pharmacology. LI. Nomenclature and structure-function relationships of cyclic nucleotide-regulated channels". Pharmacol Rev. 57 (4): 455–62. doi:10.1124/pr.57.4.8. PMID 16382102.
  7. 1 2 "Entrez Gene: CNGA4 cyclic nucleotide gated channel alpha 4".

Further reading

  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Kelliher KR, Ziesmann J, Munger SD, et al. (2003). "Importance of the CNGA4 channel gene for odor discrimination and adaptation in behaving mice". Proc. Natl. Acad. Sci. U.S.A. 100 (7): 4299–304. doi:10.1073/pnas.0736071100. PMC 153087. PMID 12649326.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Munger SD, Lane AP, Zhong H, et al. (2002). "Central Role of the CNGA4 Channel Subunit in Ca2+-Calmodulin–Dependent Odor Adaptation". Science. 294 (5549): 2172–5. doi:10.1126/science.1063224. PMC 2885906. PMID 11739959.
  • Sautter A, Zong X, Hofmann F, Biel M (1998). "An isoform of the rod photoreceptor cyclic nucleotide-gated channel β subunit expressed in olfactory neurons". Proc. Natl. Acad. Sci. U.S.A. 95 (8): 4696–701. doi:10.1073/pnas.95.8.4696. PMC 22553. PMID 9539801.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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