GJA10

GJA10
Identifiers
Aliases	GJA10, CX62, gap junction protein alpha 10
External IDs	MGI: 1339969 HomoloGene: 7733 GeneCards: GJA10
Gene location (Human)
Chr.	Chromosome 6 (human)[1]
End	89,921,760 bp[1]
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)[2]
End	32,602,760 bp[2]
Gene ontology
Molecular function	• gap junction channel activity;
Cellular component	• integral component of membrane; • gap junction; • cell junction; • plasma membrane; • connexin complex; • membrane;
Biological process	• synapse assembly; • cell communication; • gamete generation; • transmembrane transport; • response to light stimulus; • detection of light stimulus involved in visual perception;
	Sources:Amigo / QuickGO
Orthologs
	84694
	14610
	ENSG00000135355
	ENSMUSG00000051056
	Q969M2
	Q9WUS4
	NM_032602
	NM_010289
	NP_115991
	NP_034419
	Wikidata
View/Edit Human	View/Edit Mouse

Gap junction alpha-10 protein, also known as connexin-62 (Cx62), is a protein that in humans is encoded by the GJA10 gene.^[5]

Connexins, such as GJA10, are involved in the formation of gap junctions, intercellular conduits that directly connect the cytoplasms of contacting cells. Each gap junction channel is formed by docking of 2 hemichannels, each of which contains 6 connexin subunits.^[5]^[6]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000135355 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000051056 - Ensembl, May 2017
↑ "Human PubMed Reference:".
↑ "Mouse PubMed Reference:".
1 2 "Entrez Gene: gap junction protein".
↑ Söhl G, Nielsen PA, Eiberger J, Willecke K (2003). "Expression profiles of the novel human connexin genes hCx30.2, hCx40.1, and hCx62 differ from their putative mouse orthologues". Cell Commun. Adhes. 10 (1): 27–36. doi:10.1080/15419060302063. PMID 12881038.

GJA10

References

Further reading