KCNA10

KCNA10
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesKCNA10, Kcn1, Kv1.8, potassium voltage-gated channel subfamily A member 10
External IDsMGI: 3037820 HomoloGene: 4054 GeneCards: KCNA10
Gene location (Human)
Chr.Chromosome 1 (human)[1]
Band1p13.3Start110,517,217 bp[1]
End110,519,175 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

3744

242151

Ensembl

ENSG00000143105

ENSMUSG00000042861

UniProt

Q16322

B2RQA1

RefSeq (mRNA)

NM_005549

NM_001081140

RefSeq (protein)

NP_005540

NP_001074609

Location (UCSC)Chr 1: 110.52 – 110.52 MbChr 3: 107.18 – 107.2 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Potassium voltage-gated channel subfamily A member 10 also known as Kv1.8 is a protein that in humans is encoded by the KCNA10 gene.[5][5] The protein encoded by this gene is a voltage-gated potassium channel subunit.

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000143105 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000042861 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. 1 2 Gutman GA, Chandy KG, Grissmer S, Lazdunski M, McKinnon D, Pardo LA, Robertson GA, Rudy B, Sanguinetti MC, Stuhmer W, Wang X (Dec 2005). "International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels". Pharmacol Rev. 57 (4): 473–508. doi:10.1124/pr.57.4.10. PMID 16382104.

Further reading

  • Landes GM, Curran ME, Keating MT (1995). "Molecular characterization and refined genomic localization of three human potassium ion channel genes". Cytogenet. Cell Genet. 70 (3–4): 280–4. doi:10.1159/000134052. PMID 7789190.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Tian S, Liu W, Wu Y, et al. (2002). "Regulation of the voltage-gated K+ channel KCNA10 by KCNA4B, a novel beta-subunit". Am. J. Physiol. Renal Physiol. 283 (1): F142–9. doi:10.1152/ajprenal.00258.2001. PMID 12060596.
  • Orias M, Bray-Ward P, Curran ME, et al. (1997). "Genomic localization of the human gene for KCNA10, a cGMP-activated K channel". Genomics. 42 (1): 33–7. doi:10.1006/geno.1997.4712. PMID 9177773.
  • Lang R, Lee G, Liu W, et al. (2000). "KCNA10: a novel ion channel functionally related to both voltage-gated potassium and CNG cation channels". Am. J. Physiol. Renal Physiol. 278 (6): F1013–21. PMID 10836990.
  • Yao X, Tian S, Chan HY, et al. (2002). "Expression of KCNA10, a voltage-gated K channel, in glomerular endothelium and at the apical membrane of the renal proximal tubule". J. Am. Soc. Nephrol. 13 (12): 2831–9. doi:10.1097/01.ASN.0000036866.37886.C5. PMID 12444201.


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