Testosterone enantate benzilic acid hydrazone

Testosterone enantate benzilic acid hydrazone
Clinical data
Trade names	Climacteron
Synonyms	Testosterone enantate benziloylhydrazone; Testosterone 17β-enantate 3-benzilic acid hydrazone
Routes of; administration	Intramuscular injection[1][2]
Identifiers
	IUPAC name [(3Z,8R,9S,10R,13S,14S)-3-[(2-Hydroxy-2,2-diphenylacetyl)hydrazinylidene]-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl] heptanoate;
CAS Number	18625-33-7;
PubChem CID	101982710;
DrugBank	DB13947;
ChemSpider	21160607;
UNII	X8Z8A2G2Y4;
Chemical and physical data
Formula	C40H52N2O4
Molar mass	624.87 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CCCCCCC(=O)OC1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=C/C(=N\NC(=O)C(C5=CC=CC=C5)(C6=CC=CC=C6)O)/CC[C@]34C)C;
	InChI InChI=1S/C40H52N2O4/c1-4-5-6-13-18-36(43)46-35-22-21-33-32-20-19-30-27-31(23-25-38(30,2)34(32)24-26-39(33,35)3)41-42-37(44)40(45,28-14-9-7-10-15-28)29-16-11-8-12-17-29/h7-12,14-17,27,32-35,45H,4-6,13,18-26H2,1-3H3,(H,42,44)/b41-31-/t32-,33-,34-,35?,38-,39-/m0/s1; Key:PTVXYACXDYZNID-JKNBFTAXSA-N;

Testosterone enantate benzilic acid hydrazone, or testosterone 17β-enantate 3-benzilic acid hydrazone, is a synthetic, injected androgen/anabolic steroid and an androgen ester – specifically, the C17β enantate (heptanoate) ester and C3 benzilic acid hydrazone of testosterone.^[1]^[2] It was previously marketed in combination with estradiol benzoate and estradiol dienantate under the brand name Climacteron.^[2]

References

1 2 J. Elks (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 641–. ISBN 978-1-4757-2085-3.
1 2 3 Al-Imari L, Wolfman WL (September 2012). "The safety of testosterone therapy in women". J Obstet Gynaecol Can. 34 (9): 859–865. doi:10.1016/S1701-2163(16)35385-3. PMID 22971455.

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