Bolasterone

Bolasterone
Clinical data
Trade names	Myagen, Methosarb
Synonyms	U-19763; NSC-66233; 7α,17α-Dimethyltestosterone; 7α,17α-Dimethylandrost-4-en-17β-ol-3-one
Routes of; administration	By mouth
Identifiers
	IUPAC name (7R,8R,9S,10R,13S,14S,17S)-17-hydroxy-7,10,13,17-tetramethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one;
CAS Number	1605-89-6 ;
PubChem CID	102146;
ChemSpider	92280;
UNII	T7ZM08F7FU;
ChEMBL	CHEMBL259548;
ECHA InfoCard	100.015.018
Chemical and physical data
Formula	C21H32O2
Molar mass	316.485 g/mol
3D model (JSmol)	Interactive image;
	SMILES O=C4\C=C3/[C@]([C@H]2CC[C@]1([C@@H](CC[C@@]1(O)C)[C@@H]2[C@H](C)C3)C)(C)CC4;
	InChI InChI=1S/C21H32O2/c1-13-11-14-12-15(22)5-8-19(14,2)16-6-9-20(3)17(18(13)16)7-10-21(20,4)23/h12-13,16-18,23H,5-11H2,1-4H3/t13-,16+,17+,18-,19+,20+,21+/m1/s1; Key:IVFYLRMMHVYGJH-VLOLGRDOSA-N;

Bolasterone (INN, USAN) (brand names Myagen, Methosarb; former developmental code name U-19763), also known as 7α,17α-dimethyltestosterone, is a 17α-alkylated androgen/anabolic steroid (AAS) which is used in veterinary medicine.^[1]^[2] It has close structural similarity to testosterone (medication)|testosterone, and like methyltestosterone has a methyl group at C17α in order to increase oral bioavailability.^[1] In addition, it is also 7α-methylated, similar to its 7β-methylated isomer calusterone.^[1] The medication has a low to moderate ratio of anabolic to androgenic activity, similar to that of fluoxymesterone.^[3]

References

1 2 3 J. Elks (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 646–. ISBN 978-1-4757-2085-3.
↑ I.K. Morton; Judith M. Hall (6 December 2012). Concise Dictionary of Pharmacological Agents: Properties and Synonyms. Springer Science & Business Media. pp. 52–. ISBN 978-94-011-4439-1.
↑ Charles D. Kochakian (6 December 2012). Anabolic-Androgenic Steroids. Springer Science & Business Media. pp. 377, 401. ISBN 978-3-642-66353-6.

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