Cioteronel
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Synonyms | CPC-10997; Cyoctol; Ethocyn; X-Andron |
Routes of administration | By mouth, topical |
Drug class | Nonsteroidal antiandrogen |
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Formula | C16H28O2 |
Molar mass | 252.39232 g/mol |
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Cioteronel (INN, USAN) (developmental code name CPC-10997; former tentative brand names Cyoctol, Ethocyn, X-Andron) is a nonsteroidal antiandrogen (NSAA) that was never marketed.[1][2][3] It was under development between 1989 and 2001 for the topical treatment of androgenetic alopecia (male pattern baldness) and acne and for the oral treatment of benign prostatic hyperplasia; it reached phase III clinical trials for acne and phase II studies for androgenetic alopecia, but was ultimately discontinued due to poor efficacy.[3][4]
See also
References
- ↑ C.R. Ganellin; David J. Triggle (21 November 1996). Dictionary of Pharmacological Agents. CRC Press. pp. 570–. ISBN 978-0-412-46630-4.
- ↑ Daniel Lednicer (21 November 1994). The Organic Chemistry of Drug Synthesis. John Wiley & Sons. pp. 11–. ISBN 978-0-471-58959-4.
- 1 2 Tiwari, Atul; Krishna, N S; Nanda, Kamna; Chugh, Anita (2005). "Benign prostatic hyperplasia: an insight into current investigational medical therapies". Expert Opinion on Investigational Drugs. 14 (11): 1359–1372. doi:10.1517/13543784.14.11.1359. ISSN 1354-3784.
- ↑ https://adisinsight.springer.com/drugs/800003205%5Bpermanent+dead+link%5D
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