Drupanol

Drupanol
Identifiers
Chemical and physical data
Formula C18H24O
Molar mass 256.387 g/mol
3D model (JSmol)

Drupanol is a naturally occurring phenol that has been isolated from the seeds of Psoralea drupaceae.[1][2] Although drupanol is sometimes said to be the same compound as bakuchiol, the two compounds are in fact distinct; they have the same molecular formula and weight but different chemical structures and hence are structural isomers.[1] Drupanol has been found to possess androgenic and anabolic activity and hence is a phytoandrogen.[3] In contrast to drupanol, bakuchiol has been found to possess antiandrogenic activity.[4]

References

  1. 1 2 J. Elks (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. p. 120,473. ISBN 978-1-4757-2085-3.
  2. ↑ Golovina, L. A.; Nikonov, G. K. (1973). "The structure of drupanol — A new phenol from Psoralea drupaceae". Chemistry of Natural Compounds. 9 (1): 7–9. doi:10.1007/BF00580876. ISSN 0009-3130.
  3. ↑ Sasha W. Eisenman; David E. Zaurov; Lena Struwe (14 September 2012). Medicinal Plants of Central Asia: Uzbekistan and Kyrgyzstan. Springer Science & Business Media. pp. 205–. ISBN 978-1-4614-3912-7.
  4. ↑ Miao, L., Ma, S. W., Fan, G. W., Wang, H., Wang, Y. F., & Chai, L. J. (2013). Bakuchiol inhibits the androgen induced-proliferation of prostate cancer cell line LNCaP through suppression of AR transcription activity. Tianjin Journal of Traditional Chinese Medicine, 5, 012.


This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.