RPS17

RPS17
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesRPS17, DBA4, RPS17L, RPS17L1, RPS17L2, S17, ribosomal protein S17
External IDsMGI: 1309526 HomoloGene: 110867 GeneCards: RPS17
Gene location (Human)
Chr.Chromosome 15 (human)[1]
Band15q25.2Start82,536,750 bp[1]
End82,540,564 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

6218

20068

Ensembl

ENSG00000278229
ENSG00000182774

ENSMUSG00000061787

UniProt

P08708

P63276

RefSeq (mRNA)

NM_001021
NM_001199057

NM_009092

RefSeq (protein)

NP_001012

NP_033118

Location (UCSC)Chr 15: 82.54 – 82.54 MbChr 7: 81.34 – 81.35 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

40S ribosomal protein S17 is a protein that in humans is encoded by the RPS17 gene.[5][6][7]

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S17E family of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.[7]

References

  1. 1 2 3 ENSG00000182774 GRCh38: Ensembl release 89: ENSG00000278229, ENSG00000182774 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000061787 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. ↑ Feo S, Davies B, Fried M (Jun 1992). "The mapping of seven intron-containing ribosomal protein genes shows they are unlinked in the human genome". Genomics. 13 (1): 201–7. doi:10.1016/0888-7543(92)90221-D. PMID 1577483.
  6. ↑ Filipenko ML, Iantsen EI, Muravlev AI, Kopantsev EP, Karpova GG, Mertvetsov NP (Oct 1995). "[Mapping the genes for ribosomal proteins S14 and S17 on human chromosomes using cDNA from a panel of hybrid cells]". Bioorg Khim. 21 (5): 349–53. PMID 7661859.
  7. 1 2 "Entrez Gene: RPS17 ribosomal protein S17".

Further reading

  • Wool IG, Chan YL, Glück A (1996). "Structure and evolution of mammalian ribosomal proteins". Biochem. Cell Biol. 73 (11–12): 933–47. doi:10.1139/o95-101. PMID 8722009.
  • Chen IT, Roufa DJ (1989). "The transcriptionally active human ribosomal protein S17 gene". Gene. 70 (1): 107–16. doi:10.1016/0378-1119(88)90109-6. PMID 3240863.
  • Chen IT, Dixit A, Rhoads DD, Roufa DJ (1986). "Homologous ribosomal proteins in bacteria, yeast, and humans". Proc. Natl. Acad. Sci. U.S.A. 83 (18): 6907–11. doi:10.1073/pnas.83.18.6907. PMC 386619. PMID 3529092.
  • Mundus DA, Bulygin KN, Yamkovoy VI, et al. (1993). "Structural arrangement of the codon-anticodon interaction area in human placenta ribosomes. Affinity labelling of the 40S subunits by derivatives of oligoribonucleotides containing the AUG codon". Biochim. Biophys. Acta. 1173 (3): 273–82. doi:10.1016/0167-4781(93)90124-v. PMID 8318536.
  • Vladimirov SN, Ivanov AV, Karpova GG, et al. (1996). "Characterization of the human small-ribosomal-subunit proteins by N-terminal and internal sequencing, and mass spectrometry". Eur. J. Biochem. 239 (1): 144–9. doi:10.1111/j.1432-1033.1996.0144u.x. PMID 8706699.
  • Patel HR, Terada N, Gelfand EW (1996). "Rapamycin-sensitive phosphorylation of ribosomal protein S17 by p70 S6 kinase". Biochem. Biophys. Res. Commun. 227 (2): 507–12. doi:10.1006/bbrc.1996.1537. PMID 8878544.
  • Kenmochi N, Kawaguchi T, Rozen S, et al. (1998). "A map of 75 human ribosomal protein genes". Genome Res. 8 (5): 509–23. doi:10.1101/gr.8.5.509. PMID 9582194.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Ballif BA, Villén J, Beausoleil SA, et al. (2005). "Phosphoproteomic analysis of the developing mouse brain". Mol. Cell. Proteomics. 3 (11): 1093–101. doi:10.1074/mcp.M400085-MCP200. PMID 15345747.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Andersen JS, Lam YW, Leung AK, et al. (2005). "Nucleolar proteome dynamics". Nature. 433 (7021): 77–83. doi:10.1038/nature03207. PMID 15635413.
  • Yu Y, Ji H, Doudna JA, Leary JA (2005). "Mass spectrometric analysis of the human 40S ribosomal subunit: Native and HCV IRES-bound complexes". Protein Sci. 14 (6): 1438–46. doi:10.1110/ps.041293005. PMC 2253395. PMID 15883184.


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