60S ribosomal protein L27

RPL27
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesRPL27, L27, ribosomal protein L27
External IDsMGI: 98036 HomoloGene: 105144 GeneCards: RPL27
Orthologs
SpeciesHumanMouse
Entrez

6155

19942

Ensembl

n/a

ENSMUSG00000063316

UniProt

P61353

P61358

RefSeq (mRNA)

NM_000988

NM_011289

RefSeq (protein)

NP_000979
NP_001336850
NP_001336851

XP_017170385

Location (UCSC)n/aChr 11: 101.44 – 101.45 Mb
PubMed search[2][3]
Wikidata
View/Edit HumanView/Edit Mouse

60S ribosomal protein L27 is a protein that in humans is encoded by the RPL27 gene.[4][5]

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L27E family of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.[5]

References

  1. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000063316 - Ensembl, May 2017
  2. ↑ "Human PubMed Reference:".
  3. ↑ "Mouse PubMed Reference:".
  4. ↑ Jones KW, Chevrette M, Shapero MH, Fournier RE (Jun 1993). "Generation of region- and species-specific expressed gene probes from somatic cell hybrids". Nat Genet. 1 (4): 278–83. doi:10.1038/ng0792-278. PMID 1302024.
  5. 1 2 "Entrez Gene: RPL27 ribosomal protein L27".

Further reading

  • Wool IG, Chan YL, Glück A (1996). "Structure and evolution of mammalian ribosomal proteins". Biochem. Cell Biol. 73 (11–12): 933–47. doi:10.1139/o95-101. PMID 8722009.
  • Miki Y, Swensen J, Shattuck-Eidens D, et al. (1994). "A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1". Science. 266 (5182): 66–71. doi:10.1126/science.7545954. PMID 7545954.
  • Harshman K, Bell R, Rosenthal J, et al. (1995). "Comparison of the positional cloning methods used to isolate the BRCA1 gene". Hum. Mol. Genet. 4 (8): 1259–66. doi:10.1093/hmg/4.8.1259. PMID 7581362.
  • Gallagher RA, McClean PM, Malik AN (1994). "Cloning and nucleotide sequence of a full length cDNA encoding ribosomal protein L27 from human fetal kidney". Biochim. Biophys. Acta. 1217 (3): 329–32. doi:10.1016/0167-4781(94)90295-x. PMID 8148381.
  • Uechi T, Tanaka T, Kenmochi N (2001). "A complete map of the human ribosomal protein genes: assignment of 80 genes to the cytogenetic map and implications for human disorders". Genomics. 72 (3): 223–30. doi:10.1006/geno.2000.6470. PMID 11401437.
  • Andersen JS, Lyon CE, Fox AH, et al. (2002). "Directed proteomic analysis of the human nucleolus". Curr. Biol. 12 (1): 1–11. doi:10.1016/S0960-9822(01)00650-9. PMID 11790298.
  • Yoshihama M, Uechi T, Asakawa S, et al. (2002). "The human ribosomal protein genes: sequencing and comparative analysis of 73 genes". Genome Res. 12 (3): 379–90. doi:10.1101/gr.214202. PMC 155282. PMID 11875025.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Andersen JS, Lam YW, Leung AK, et al. (2005). "Nucleolar proteome dynamics". Nature. 433 (7021): 77–83. doi:10.1038/nature03207. PMID 15635413.
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