Buclizine

Buclizine
Clinical data
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ATC code
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ECHA InfoCard 100.001.317 Edit this at Wikidata
Chemical and physical data
Formula C28H33ClN2
Molar mass 433.028 g/mol
3D model (JSmol)
Chirality Racemic mixture
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Buclizine is an antihistamine and anticholinergic of the diphenylmethylpiperazine group. It is considered to be an antiemetic, similar to meclizine.[1]

In the United Kingdom, buclizine is one of three drugs contained in Migraleve tablets, marketed by McNeil Healthcare at migraine sufferers.[2]

References

  1. ↑ Mostafa GA, Al-Badr AA (2011). "Buclizine". Profiles Drug Subst Excip Relat Methodol. Profiles of Drug Substances, Excipients and Related Methodology. 36: 1–33. doi:10.1016/B978-0-12-387667-6.00001-4. ISBN 9780123876676. PMID 22469258.
  2. ↑ Behrendt WA, Cserepes J (1985). "Acute toxicity and analgesic action of a combination of buclizine, codeine and paracetamol ('Migraleve') in tablet and suppository form in rats". Pharmatherapeutica. 4 (5): 322–31. PMID 4070325.
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