Dexbrompheniramine

Dexbrompheniramine
Clinical data
Trade names Drixoril, Conex, Dixaphedrine
AHFS/Drugs.com Multum Consumer Information
Pregnancy
category
  • US: C (Risk not ruled out)
    Routes of
    administration    		 Oral
    ATC code
    Legal status
    Legal status
    Pharmacokinetic data
    Elimination half-life 25 hours
    Identifiers
    CAS Number
    PubChem CID
    IUPHAR/BPS
    DrugBank
    ChemSpider
    UNII
    ChEBI
    ChEMBL
    ECHA InfoCard 100.004.595 Edit this at Wikidata
    Chemical and physical data
    Formula C16H19BrN2
    Molar mass 319.24 g/mol
    3D model (JSmol)
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    Dexbrompheniramine is an antihistamine with anticholinergic properties[1] used to treat allergic conditions such as hay fever or urticaria. It is the pharmacologically active dextrorotatory isomer of brompheniramine. It was formerly marketed in combination with pseudoephedrine under the name Drixoral in the US and Canada.

    Dexbrompheniramine is a first generation antihistamine that reduces the effects of the neurotransmitter histamine in the body; sneezing, itching, watery eyes, and runny nose.

    Interactions

    MAO inhibitors within 14 days. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.

    Potassium (Cytra, Epiklor, K-Lyte, K-Phos, Kaon, Klor-Con, Polycitra, Urocit-K).

    Drinking alcohol can increase side effects of dexbrompheniramine.

    References

    1. ↑ Löfkvist, T. (1978). "A comparative evaluation of oral decongestants in the treatment of vasomotor rhinitis". The Journal of international medical research. 6 (1): 56–60. doi:10.1177/030006057800600110. PMID 627306.
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