Bamipine

Bamipine
Clinical data
Trade names Soventol
AHFS/Drugs.com International Drug Names
Routes of
administration		 Oral?, topical
ATC code
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
ECHA InfoCard 100.023.261 Edit this at Wikidata
Chemical and physical data
Formula C19H24N2
Molar mass 280.407 g/mol
3D model (JSmol)
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Bamipine (trade name Soventol) is a pharmaceutical drug acting as an H1 antihistamine with anticholinergic properties. It is used as an antipruritic ointment.[1] No oral use is known.[2]

Adverse effects

Side effects are typical of an old (first-generation) antihistamine: tiredness in adults, agitation in children, mydriasis (dilation of the pupils). These effects are rare when bamipine is applied topically as an ointment. Allergic and hypersensitivity reactions are also rare. Acute eczema can be worsened by bamipine ointment.[3]

Contraindications and interactions

No clinically relevant contraindications or interactions with other drugs are known.[3]

Pharmacology

Pharmacokinetics

When applied topically, the maximal effect is reached after 20 to 60 minutes and lasts up to 48 hours. Bamipine is not absorbed through intact skin in relevant doses.[3]

References

  1. ↑ , M Pairet, MP Pieper, CJM Meade, "Pharmaceutical compositions containing tiotropium salts and antihistamines and their use", published 2001
  2. ↑ International Drug Names: Bamipine.
  3. 1 2 3 Haberfeld, H, ed. (2015). Austria-Codex (in German). Vienna: Österreichischer Apothekerverlag. Soventol-Gel.
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