MYH7B

MYH7B
Identifiers
AliasesMYH7B, MHC14, MYH14, myosin, heavy chain 7B, cardiac muscle, beta, myosin heavy chain 7B
External IDsMGI: 3710243 HomoloGene: 66117 GeneCards: MYH7B
Gene location (Human)
Chr.Chromosome 20 (human)[1]
Band20q11.22Start34,975,403 bp[1]
End35,002,437 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

57644

668940

Ensembl

ENSG00000078814

ENSMUSG00000074652

UniProt

Q5JW45

A2AQP0

RefSeq (mRNA)

NM_020884

NM_001085378

RefSeq (protein)

NP_065935

NP_001078847

Location (UCSC)Chr 20: 34.98 – 35 MbChr 2: 155.61 – 155.63 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Myosin-7B also known as myosin, heavy chain 7B is a protein that in humans is encoded by the MYH7B gene.[5][6]

Function

MYH7B is a slow-twitch myosin.[6]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000078814 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000074652 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. ↑ Nagase T, Kikuno R, Ishikawa K, Hirosawa M, Ohara O (April 2000). "Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 7 (2): 143–50. doi:10.1093/dnares/7.2.143. PMID 10819331.
  6. 1 2 Desjardins PR, Burkman JM, Shrager JB, Allmond LA, Stedman HH (April 2002). "Evolutionary implications of three novel members of the human sarcomeric myosin heavy chain gene family". Mol. Biol. Evol. 19 (4): 375–93. doi:10.1093/oxfordjournals.molbev.a004093. PMID 11919279.

Further reading

  • Rossi AC, Mammucari C, Argentini C, et al. (2010). "Two novel/ancient myosins in mammalian skeletal muscles: MYH14/7b and MYH15 are expressed in extraocular muscles and muscle spindles". J. Physiol. 588 (Pt 2): 353–64. doi:10.1113/jphysiol.2009.181008. PMC 2821527. PMID 19948655.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Deloukas P, Matthews LH, Ashurst J, et al. (2001). "The DNA sequence and comparative analysis of human chromosome 20". Nature. 414 (6866): 865–71. doi:10.1038/414865a. PMID 11780052.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • McGuigan K, Phillips PC, Postlethwait JH (2004). "Evolution of sarcomeric myosin heavy chain genes: evidence from fish". Mol. Biol. Evol. 21 (6): 1042–56. doi:10.1093/molbev/msh103. PMID 15014174.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Hu Z, Liang J, Wang Z, et al. (2009). "Common genetic variants in pre-microRNAs were associated with increased risk of breast cancer in Chinese women". Hum. Mutat. 30 (1): 79–84. doi:10.1002/humu.20837. PMID 18634034.


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