CD302

CD302
Identifiers
AliasesCD302, BIMLEC, CLEC13A, DCL-1, DCL1, CD302 molecule
External IDsMGI: 1913455 HomoloGene: 8919 GeneCards: CD302
Gene location (Human)
Chr.Chromosome 2 (human)[1]
Band2q24.2Start159,768,630 bp[1]
End159,798,255 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

9936

66205

Ensembl

ENSG00000241399

ENSMUSG00000060703

UniProt

Q8IX05

Q9DCG2

RefSeq (mRNA)

NM_014880
NM_001198763
NM_001198764

NM_001290660
NM_025422

RefSeq (protein)

NP_001185692
NP_001185693
NP_055695

NP_001277589
NP_079698

Location (UCSC)Chr 2: 159.77 – 159.8 MbChr 2: 60.25 – 60.28 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

The CD302 antigen also known as C-type lectin domain family 13 member A is a protein that in humans is encoded by the CD302 gene.[5][6]

Function

CD302 is a C-type lectin receptor involved in cell adhesion and migration, as well as endocytosis and phagocytosis.[7]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000241399 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000060703 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. ↑ Nomura N, Miyajima N, Sazuka T, Tanaka A, Kawarabayasi Y, Sato S, Nagase T, Seki N, Ishikawa K, Tabata S (1994). "Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1". DNA Res. 1 (1): 27–35. doi:10.1093/dnares/1.1.27. PMID 7584026.
  6. ↑ Nomura N, Miyajima N, Sazuka T, Tanaka A, Kawarabayasi Y, Sato S, Nagase T, Seki N, Ishikawa K, Tabata S (1994). "Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1 (supplement)". DNA Res. 1 (1): 47–56. doi:10.1093/dnares/1.1.47. PMID 7584028.
  7. ↑ Kato M, Khan S, d'Aniello E, McDonald KJ, Hart DN (November 2007). "The novel endocytic and phagocytic C-Type lectin receptor DCL-1/CD302 on macrophages is colocalized with F-actin, suggesting a role in cell adhesion and migration". J. Immunol. 179 (9): 6052–63. doi:10.4049/jimmunol.179.9.6052. PMID 17947679.

Further reading

  • Hillier LW, Graves TA, Fulton RS, et al. (2005). "Generation and annotation of the DNA sequences of human chromosomes 2 and 4". Nature. 434 (7034): 724–31. doi:10.1038/nature03466. PMID 15815621.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Yang S, Noble CG, Yang D (2009). "Characterization of DLC1-SAM equilibrium unfolding at the amino acid residue level". Biochemistry. 48 (19): 4040–9. doi:10.1021/bi9000936. PMID 19317456.
  • Kato M, Khan S, Gonzalez N, et al. (2003). "Hodgkin's lymphoma cell lines express a fusion protein encoded by intergenically spliced mRNA for the multilectin receptor DEC-205 (CD205) and a novel C-type lectin receptor DCL-1". J. Biol. Chem. 278 (36): 34035–41. doi:10.1074/jbc.M303112200. PMID 12824192.
  • Bonaldo MF, Lennon G, Soares MB (1996). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.


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