List of U.S. Highways in South Carolina

U.S. Highways of South Carolina
U.S. Route 1 marker U.S. Route 76 marker U.S. Route 178 marker
Highway marker for U.S. Highways in South Carolina
System information
Maintained by SCDOT
Formed November 11, 1926 (1926-11-11)[1]
Highway names
US Highways U.S. Highway nn (US nn)
System links

There are 23 U.S. Highways that exist entirely or partially in the U.S. state of South Carolina. In South Carolina, all U.S. Highways are maintained by the South Carolina Department of Transportation (SCDOT).

Mainline highways

Number Length (mi) Length (km) Southern or western terminus Northern or eastern terminus Formed Removed Notes
US 1 170.1273.7 Georgia state line at North AugustaNorth Carolina state line near Wallace 01926-01-011926current Travels north-south along the sandhills region; connecting the cities of North Augusta, Aiken, Columbia, and Camden. South of Camden, it parallels with I-20.
US 15 158.6255.2 WalterboroNorth Carolina state line at McColl 01935-01-011935current Travels north-south, connecting the cities of Walterboro, Sumter, and Bennettsville.
US 17 221.0355.7 Georgia state line near LimehouseNorth Carolina state line near Little River 01927-01-011927current Travels north-south along the coastal plain area, connecting the cities of Hardeeville, Charleston, Georgetown, and Myrtle Beach.
US 21 232.2373.7 Hunting Island State ParkNorth Carolina state line near Little River 01926-01-011926current Travels north-south, connecting the cities of Beaufort, Orangeburg, Columbia, and Rock Hill. North of Columbia, it parallels with I-77.
US 25 140.3225.8 Georgia state line in North AugustaNorth Carolina state line near Travelers Rest 01926-01-011926current Travels north-south in the western part of the state, connecting the cities of North Augusta, Greenwood, and Greenville.
US 29 109.1175.6 Georgia state line near Holland StoreNorth Carolina state line at Blacksburg 01927-01-011927current Travels north-south in the Upstate area, parallel to I-85. It connects the cities of Anderson, Greenville, and Spartanburg.
US 52 161.0259.1 CharlestonNorth Carolina state line near Cheraw 01980-10-201980current Travels north-south, connecting the cities of Charleston, Lake City, Florence, and Darlington.
US 76 297.9479.4 Georgia state line near WestminsterNorth Carolina state line near Nichols 01926-01-011926current Longest US Highway in the state, going east-west; it connects the cities Anderson, Columbia, Sumter, and Florence.
US 78 141.0226.9 Georgia state line near North AugustaCharleston 01926-01-011926current Travels east-west, connecting the cities of North Augusta, Aiken, Bamberg, and Charleston.
US 117 45.072.4 ConwayNorth Carolina state line near Little River 01932-01-01193201935-01-011935 Replaced by US 501 and US 17.
US 123 57.492.4 Georgia state line near WestminsterGreenville 01968-01-011968current Travels north-south in the Upstate area, connecting the cities of Westminster and Greenville.
US 176 218.7352.0 North Carolina state line near LandrumGoose Creek 01926-01-011926current Travels east-west, parallel to I-26. It connects the cities of Spartanburg, Union, and Columbia.
US 178 232.7374.5 RidgevilleNorth Carolina state line near Rocky Bottom 01932-01-011932current Travels east-west, connecting the cities of Anderson, Greenwood, and Orangeburg.
US 217 24.439.3 Pee DeeNorth Carolina state line near Dillon 01927-01-01192701932-01-011932 Replaced by US 301.
US 221 125.9202.6 Georgia state line near Clarks HillNorth Carolina state line at Chesnee 01932-01-011932current Travels north-south within the Piedmont area, connecting the cities of Greenwood and Spartanburg.
US 276 34.255.0 North Carolina state line near ClevelandMauldin 01932-01-011932current Shortest US Highway in the state, going east-west; it goes through the city of Greenville.
US 278 146.0235.0 Georgia state line near North AugustaHilton Head Island 01965-01-011965current Travels east-west, connecting the cities of North Augusta and Hilton Head Island.
US 301 190.3306.3 Georgia state line near AllendaleNorth Carolina state line near Dillon 01932-01-011932current Travels north-south, loosely parallel to I-95. It connects the cities of Orangeburg, Florence, and Dillon.
US 321 227.4366.0 HardeevilleNorth Carolina state line near Clover 01930-01-011930current Travels north-south, connecting the cities of Hardeeville, Columbia, and York.
US 378 210.9339.4 Georgia state line near McCormickConway 01952-01-011952current Travels east-west, connecting the cities of Columbia, Sumter, and Conway.
US 401 77.2124.2 SumterNorth Carolina state line near McColl 01957-01-011957current Travels north-south, connecting the cities of Sumter, Darlington, and Bennettsville.
US 501 74.0119.1 Myrtle BeachNorth Carolina state line near Dillon 01935-01-011935current Travels north-south through the Grand Strand area, connecting the cities of Myrtle Beach, Conway, and Dillon.
US 521 173.5279.2 GeorgetownNorth Carolina state line at Indian Land 01932-01-011932current Travels north-south, connecting the cities of Georgetown, Sumter, Camden, and Lexington.
US 601 181.4291.9 TarboroNorth Carolina state line at Pageland 01927-01-011927current Travels north-south,connecting the cities of Bamberg, Orangeburg, Camden, and Pageland.
US 701 61.599.0 GeorgetownNorth Carolina state line near Loris 01932-01-011932current Travels north-south through the Grand Strand area, connecting the cities of Georgetown and Conway.
  •       Former

Special routes

Number Length (mi) Length (km) Southern or western terminus Northern or eastern terminus Formed Removed Notes

US 15 Alt.
WalterboroNorth Carolina state line near McColl 01937-01-01193701946-01-011946 The entire route was in concurrency with US 15 in South Carolina.

US 15 Alt.
SumterSociety Hill 01955-01-01195501957-01-011957 Replaced by US 401.

US 15 Bus.
6.610.6 Hartsville 01969-01-011969current Routed along Fifth Street.

US 15 Bus.
Bennettsville 01952-01-01195201990-01-011990 Was routed along Main Street and Tyson Avenue, in concurrency with US 401 Bus. It was replaced by SC 385.

US 17 Alt.
6.710.8 Georgia state line near Savannah, GeorgiaLimehouse 01955-01-01195501994-01-011994 Provided an alternate route from Savannah, via the Talmadge Memorial Bridge. Was reassigned as mainline US 17.

US 17 Alt.
123.4198.6 PocotaligoGeorgetown 01952-01-011952current Travels north-south,connecting the cities of Walterboro, Summerville, Moncks Corner and Georgetown.

US 17 Bus.
4.26.8 Mount Pleasant 01967-01-01196701992-01-011992 Was routed along Coleman Boulevard and Georgetown Highway (Chuck Dawley Boulevard) in concurrency with US 701 Bus. It was replaced by SC 703 and BS 526.

US 17 Bus.
22.836.7 Murrells InletMyrtle Beach 01967-01-011967current Connects the downtown areas of Murrells Inlet, Garden City, Surfside Beach and Myrtle Beach.

US 21 Bus.
3.25.1 Beaufort 01967-01-011967current Routed along Sea Island Parkway, Carteret Street and Boundary Street.

US 21 Bus.
3.35.3 Orangeburg 01950-01-01195001967-01-011967 Was routed along Broughton Street (in concurrency with US 178 Bus.) and Columbia Road.

US 21 Bus.
2.94.7 Orangeburg 01967-01-011967current Routed along Rowesville Road, Charleston Highway and Magnolia Street.

US 21 Bus.
6.710.8 Rock Hill 01950-01-01195002013-01-012013 Was routed along Main Street, Albright Road, Black Street, Oakland Avenue, and Cherry Road, through downtown Rock Hill. It was decommissioned at the request of Rock Hill to gain ownership and maintenance oversight.[2][3]

US 21 Bus.
6.19.8 Fort Mill 01948-01-011948current It is routed along Spratt Street, White Street, Old Nations Road, and Springfield Parkway, through downtown Fort Mill.

US 25 Bus.
2.84.5 Georgia state line in North Augusta 01961-01-011961current Only business loop that crosses the Georgia–South Carolina state line.

US 25 Bus.
2.84.5 Greenwood 01969-01-011969current

US 25 Bus.
4.57.2 Ware Shoals 01963-01-011963current

US 25 Bus.
Greenville 01969-01-01196901995-01-011995 Former business loop through downtown Greenville; replaced in parts by US 123, US 276, SC 20 and SC 291.

US 29 Alt.
Greenville 01938-01-01193801948-01-011948 Was an alternate route through downtown Greenville, was downgraded to secondary roads.

US 29 Alt.
SpartanburgBlacksburg 01955-01-01195501962-01-011962 Was a redesignation of mainline US 29 between Spartanburg and Blacksburg; after I-85 was established, it was reverted to US 29.

US 29 Bus.
6.410.3 Anderson 01947-01-011947current

US 29 Bus.
Greenville 01958-01-01195801962-01-011962

US 52 Bus.
4.06.4 Darlington 01974-01-011974current

US 76 Bus.
Seneca 01958-01-01195802000-01-012000

US 76 Bus.
3.86.1 Laurens 01982-01-011982current

US 76 Bus.
Newberry 01952-01-01195202001-01-012001

US 76 Bus.
5.99.5 Sumter 01959-01-011959current

US 78 Bus.
0.71.1 Blackville 01981-01-011981current

US 123 Alt.
Greenville 01950-01-01195001972-01-011972 Replaced by SC 124.

US 123 Bus.
Seneca 01958-01-01195802000-01-012000 Was routed along North First Street.

US 123 Bus.
Easley 01958-01-01195801964-01-011964 Was routed along Main Street and Liberty Drive. It was replaced by SC 93.

US 176 Alt.
Spartanburg 01938-01-01193801948-01-011948 Traversed in downtown Spartanburg, along Magnolia and Howard streets. Some map inserts of the time list it as "Optional US 176;" was downgraded to secondary roads.

US 176 Bus.
Union 01958-01-01195801990-01-011990 Was routed along Pinckney Street and Thompson Boulevard. It was replaced by SC 18.

US 178 Bus.
3.96.3 Greenwood 01949-01-011949current

US 178 Bus.
4.97.9 Orangeburg 01970-01-011970current

US 221 Alt.
5.38.5 ChesneeNorth Carolina state line near Cowpens National Battlefield 01941-01-011941current Provides an alternate route from Chesnee to Forest City, NC.

US 276 Bus.
Greenville 01948-01-01194801970-01-011970

US 278 Bus.
8.814.2 Hilton Head 01998-01-011998current

US 321 Bus.
4.36.9 Winnsboro 01952-01-011952current

US 321 Bus.
3.04.8 Chester 01964-01-011964current

US 321 Bus.
2.64.2 York 01958-01-011958current

US 378 Bus.
6.610.6 Sumter 01961-01-011961 Was routed along Broad Street, Liberty Street and Myrtle Beach Boulevard.

US 378 Bus.
2.64.2 Lake City 01958-01-011958current Routed along Main Street (with SC 341) and Church Street/Myrtle Beach Highway.

US 401 Bus.
Bennettsville 01958-01-01195801990-01-011990 Was routed along Main Street and Tyson Avenue, in concurrency with US 15 Bus. It was replaced by SC 385.

US 501 Bus.
4.47.1 Conway 01964-01-011964current

US 501 Bus.
6.610.6 Marion 01964-01-011964current

US 521 Bus.
1.42.3 Kershaw

US 521 Bus.
3.86.1 Lancaster 01965-01-011965current

US 701 Bus.
4.26.8 Mount Pleasant 01967-01-01196701992-01-011992 Was routed along Coleman Boulevard and Georgetown Highway (Chuck Dawley Boulevard) in concurrency with US 17 Bus. It was replaced by SC 703 and BS 526.

US 701 Bus.
0.10.2 North Carolina state line near Tabor City, North Carolina 01960-01-011960current Only business loop that crosses the North Carolina–South Carolina state line
  •       Former

See also

  • South Carolina portal
  • U.S. Roads portal

References

  1. Bureau of Public Roads & American Association of State Highway Officials (November 11, 1926). United States System of Highways Adopted for Uniform Marking by the American Association of State Highway Officials (Map). 1:7,000,000. Washington, DC: United States Geological Survey. OCLC 32889555. Retrieved November 7, 2013 via University of North Texas Libraries.
  2. "Binder-all applications May 2013" (PDF). AASHTO. May 2013. p. 301. Retrieved July 7, 2013.
  3. Special Committee on U.S. Route Numbering (May 4, 2013). "Special Committee on US Route Numbering Report to SCOH on May 3, 2013 Meeting" (PDF) (Report). Washington, DC: American Association of State Highway and Transportation Officials. p. 8. Archived from the original on October 16, 2017. Retrieved July 7, 2013.
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