Thiobarbital

Thiobarbital
Identifiers
CAS Number
PubChem CID
ChemSpider
ECHA InfoCard 100.000.929 Edit this at Wikidata
Chemical and physical data
Formula C8H12N2O2S
Molar mass 200.259
3D model (JSmol)
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Thiobarbital is a drug which is a barbiturate derivative. It is the thiobarbiturate analogue of barbital.

Synthesis

Thiobarbital synthesis:[1][2]

It is of note that although the drug can be prepared by the above route (cf e.g. thialbarbital), rxn of barbital with phosphorus pentasulfide constitutes an alternative route to thiobarbital.

References

  1. ↑ Fischer, E.; Dilthey, A. (1904). "Ueber C-Dialkylbarbitursäuren und über die Ureïde der Dialkylessigsäuren". Justus Liebig's Annalen der Chemie. 335 (3): 334. doi:10.1002/jlac.19043350303.
  2. ↑ Carrington, H. C. (1944). "45. The action of phosphorus pentasulphide on barbituric acids". Journal of the Chemical Society (Resumed): 124. doi:10.1039/JR9440000124.


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