''N''-Ethylpentylone

N-Ethylpentylone
Clinical data
ATC code
  • none
Legal status
Legal status
Identifiers
CAS Number
PubChem CID
ChemSpider
Chemical and physical data
Formula C14H19NO3
Molar mass 249.31 g·mol−1
3D model (JSmol)

N-Ethylpentylone (β-keto-ethylbenzodioxolylpentanamine, βk-ethyl-K, βk-EBDP, ephylone) is a substituted cathinone and stimulant drug which was developed in the 1960s.[1][2]

It has been reported as a novel designer drug in several countries including South Africa,[3] New Zealand,[4] the United States,[5] and Australia.[6]

A doctor, David Caldicott, has said ephylone "can cause circulation problems, lethal heart palpitations and hallucinations". [7] It has been linked to a number of overdose deaths[8][9] and mass-casualty incidents,[10][11] and has increasingly been mis-sold as MDMA.[12]

Legality

In the United States, N-ethylpentylone is a Schedule I controlled substance.[13]

See also

References

  1. ↑ GB 1085135, "Substituted phenyl-α-amino ketones", published 1969, assigned to Boehringer Sohn Ingelheim
  2. ↑ Wood MR, Bernal I, Lalancette RA (October 2017). "The hydrochloride hydrates of pentylone and dibutylone and the hydrochloride salt of ephylone: the structures of three novel designer cathinones". Structural Chemistry. 28 (5): 1369–1376. doi:10.1007/s11224-017-0951-x. ISSN 1040-0400.
  3. ↑ Umraw A, Pillay K (15 April 2016). "No antidote yet for killer drug's special ingredient". The Witness.
  4. ↑ "This summer's crap drug: N-ethylpentylone". KnowYourStuffNZ. Retrieved 2 April 2018.
  5. ↑ Thirakul P, Hair LS, Bergen KL, Pearson JM (May 2017). "Clinical Presentation, Autopsy Results and Toxicology Findings in an Acute N-Ethylpentylone Fatality". Journal of Analytical Toxicology. 41 (4): 342–346. doi:10.1093/jat/bkx004. PMID 28137731.
  6. ↑ Pill testing at festivals has hidden benefits that could reduce drug taking, Claudia Long, ABC News Online, 2018-07-20
  7. ↑ "Arnica, metal paint and Polish toothpaste: Festival pill test comes back with all sorts". ABC News. 30 April 2018. Retrieved 2018-09-17.
  8. ↑ Stewart M (9 March 2018). "Deadly new Wellington drug ring busted as police seize cash, cars, and drugs". Stuff.co.nz.
  9. ↑ Thirakul, Phoutthasone; s. Hair, Laura; l. Bergen, Kirstin; m. Pearson, Julia (2017). "Clinical Presentation, Autopsy Results and Toxicology Findings in an AcuteN-Ethylpentylone Fatality". Journal of Analytical Toxicology. 41 (4): 342–346. doi:10.1093/jat/bkx004. PMID 28137731.
  10. ↑ "13 hospitalised in Christchurch after taking drugs they thought were MDMA". Newshub NZ. Retrieved 14 March 2018.
  11. ↑ Krotulski, Alex J.; Papsun, Donna M.; Martinis, De; S, Bruno; Mohr, Amanda L. A.; Logan, Barry K. (2018). "N-Ethyl Pentylone (Ephylone) Intoxications: Quantitative Confirmation and Metabolite Identification in Authentic Human Biological Specimens". Journal of Analytical Toxicology. 42 (7): 467–475. doi:10.1093/jat/bky025. PMID 29618077.
  12. ↑ "Thousands have drugs tested at festivals". BBC News. 3 September 2018. Retrieved 3 September 2018.
  13. ↑ "Schedules of Controlled Substances: Temporary Placement of N-Ethylpentylone in Schedule I". Federal Register. June 13, 2018.

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