Pindobind

{{Chembox | ImageFile = Pindobind.svg | ImageSize = 200px | IUPACName = 2-Bromo-N-[4-(2-{[2-hydroxy-3-(1H-indol-4-yloxy)propyl]amino}-2-propanyl)-1-methylcyclohexyl]acetamide | OtherNames = |Section1=!Identifiers |-

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Chemical formula

| C23H34BrN3O3 |- | Molar mass | 480.45 g·mol−1 |- |Section3= }}

Pindobind is a compound developed by researchers associated with Stanford University,[1] identified as a central nervous system depressant,[2] which generated a response in animals reducing offensive actions such as chasing, while also notably reducing tendencies of the test animal to evade when stimulated to do so.[2] It acts as an irreversible beta blocker and irreversible 5-HT1A receptor antagonist.

See also

References

  1. ↑ Peroutka, Stephen J.; Pitha, Josef (Jul 20, 1993), Method for relieving anxiety using 5-hydroxytryptamine-1a-receptor-binding compounds, retrieved 2016-06-04
  2. 1 2 Bell, R; Hobson, H (1993). "Effects of pindobind 5-hydroxytryptamine1A (5-HT1A), a novel and potent 5-HT1A antagonist, on social and agonistic behaviour in male albino mice". Pharmacology Biochemistry and Behavior. 46 (1): 67–72. doi:10.1016/0091-3057(93)90318-N. PMID 8255924.
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