60S ribosomal protein L4

60S ribosomal protein L4 is a protein that in humans is encoded by the RPL4 gene.[5][6][7]

RPL4
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesRPL4, L4, Ribosomal protein L4
External IDsOMIM: 180479 MGI: 1915141 HomoloGene: 748 GeneCards: RPL4
Gene location (Human)
Chr.Chromosome 15 (human)[1]
Band15q22.31Start66,498,015 bp[1]
End66,524,532 bp[1]
RNA expression pattern


More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

6124

67891

Ensembl

ENSG00000174444

ENSMUSG00000032399

UniProt

P36578

Q9D8E6

RefSeq (mRNA)

NM_000968

NM_024212

RefSeq (protein)

NP_000959

NP_077174

Location (UCSC)Chr 15: 66.5 – 66.52 MbChr 9: 64.17 – 64.18 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L4E family of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.[7]

References

  1. GRCh38: Ensembl release 89: ENSG00000174444 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000032399 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Kenmochi N, Kawaguchi T, Rozen S, Davis E, Goodman N, Hudson TJ, Tanaka T, Page DC (Aug 1998). "A map of 75 human ribosomal protein genes". Genome Res. 8 (5): 509–23. doi:10.1101/gr.8.5.509. PMID 9582194.
  6. Bagni C, Mariottini P, Annesi F, Amaldi F (Feb 1994). "Human ribosomal protein L4: cloning and sequencing of the cDNA and primary structure of the protein". Biochim Biophys Acta. 1216 (3): 475–8. doi:10.1016/0167-4781(93)90017-8. PMID 8268230.
  7. "Entrez Gene: RPL4 ribosomal protein L4".

Further reading



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