60S ribosomal protein L23

60S ribosomal protein L23 is a protein that in humans is encoded by the RPL23 gene.[5][6]

RPL23
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesRPL23, L23, rpL17, ribosomal protein L23
External IDsOMIM: 603662 MGI: 1929455 HomoloGene: 68103 GeneCards: RPL23
Gene location (Human)
Chr.Chromosome 17 (human)[1]
Band17q12Start38,847,860 bp[1]
End38,853,764 bp[1]
RNA expression pattern


More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

9349

65019

Ensembl

ENSG00000125691

ENSMUSG00000071415

UniProt

P62829

P62830

RefSeq (mRNA)

NM_000978

NM_022891

RefSeq (protein)

NP_000969

NP_075029

Location (UCSC)Chr 17: 38.85 – 38.85 MbChr 11: 97.78 – 97.78 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L14P family of ribosomal proteins. It is located in the cytoplasm. This gene has been referred to as RPL17 because the encoded protein shares amino acid identity with ribosomal protein L17 from Saccharomyces cerevisiae; however, its official symbol is RPL23. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.[6]

References

  1. GRCh38: Ensembl release 89: ENSG00000125691 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000071415 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Herault Y, Michel D, Chatelain G, Brun G (Aug 1991). "cDNA and predicted amino acid sequences of the human ribosomal protein genes rpS12 and rpL17". Nucleic Acids Res. 19 (14): 4001. doi:10.1093/nar/19.14.4001. PMC 328500. PMID 1861993.
  6. "Entrez Gene: RPL23 ribosomal protein L23".

Further reading


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