EIF3M

Eukaryotic translation initiation factor 3, subunit M (eIF3m) also known as PCI domain containing 1 (herpesvirus entry mediator) (PCID1), is a protein that in humans is encoded by the EIF3M gene.[5][6]

EIF3M
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesEIF3M, B5, PCID1, TANGO7, hfl-B5, GA17, eukaryotic translation initiation factor 3 subunit M
External IDsOMIM: 609641 MGI: 1351744 HomoloGene: 4639 GeneCards: EIF3M
Gene location (Human)
Chr.Chromosome 11 (human)[1]
Band11p13Start32,583,798 bp[1]
End32,606,264 bp[1]
RNA expression pattern


More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

10480

98221

Ensembl

ENSG00000149100

ENSMUSG00000027170

UniProt

Q7L2H7

Q99JX4

RefSeq (mRNA)

NM_001307929
NM_006360

NM_145380

RefSeq (protein)

NP_001294858
NP_006351

NP_663355

Location (UCSC)Chr 11: 32.58 – 32.61 MbChr 2: 105 – 105.02 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

HFLB5 encodes a broadly expressed protein containing putative membrane fusion domains that acts as a receptor or coreceptor for entry of herpes simplex virus (HSV).[5][7]

See also

References

  1. GRCh38: Ensembl release 89: ENSG00000149100 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000027170 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: PCID1 PCI domain containing 1 (herpesvirus entry mediator)".
  6. Gawin B, Niederführ A, Schumacher N, Hummerich H, Little PF, Gessler M (November 1999). "A 7.5 Mb sequence-ready PAC contig and gene expression map of human chromosome 11p13-p14.1". Genome Res. 9 (11): 1074–86. doi:10.1101/gr.9.11.1074. PMC 310838. PMID 10568747.
  7. Perez A, Li QX, Perez-Romero P, Delassus G, Lopez SR, Sutter S, McLaren N, Fuller AO (June 2005). "A new class of receptor for herpes simplex virus has heptad repeat motifs that are common to membrane fusion proteins". J. Virol. 79 (12): 7419–30. doi:10.1128/JVI.79.12.7419-7430.2005. PMC 1143644. PMID 15919898.

Further reading

  • Overview of all the structural information available in the PDB for UniProt: Q7L2H7 (Eukaryotic translation initiation factor 3 subunit M) at the PDBe-KB.


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