60S ribosomal protein L17

60S ribosomal protein L17 is a protein that in humans is encoded by the RPL17 gene.[3][4][5]

RPL17
Available structures PDB Human UniProt search: PDBe RCSB List of PDB id codes 4UG0, 4V6X, 5AJ0, 4V5Z, 4UJD, 5A8L, 4D67, 3J92, 4D5Y, 4UJE, 4UJC
Identifiers
Aliases	RPL17, L17, PD-1, RPL23, ribosomal protein L17
External IDs	OMIM: 603661 HomoloGene: 115574 GeneCards: RPL17
Gene location (Human) Chr. Chromosome 18 (human)[1] Band 18q21.1 Start 49,488,453 bp[1] End 49,492,523 bp[1]
Gene ontology Molecular function • GO:0001948 protein binding • structural constituent of ribosome • RNA binding Cellular component • cytosol • ribosome • large ribosomal subunit • intracellular • cytosolic large ribosomal subunit • cell nucleus Biological process • viral transcription • SRP-dependent cotranslational protein targeting to membrane • translational initiation • nuclear-transcribed mRNA catabolic process, nonsense-mediated decay • rRNA processing • protein biosynthesis • cytoplasmic translation Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	6139	n/a
Ensembl	ENSG00000265681	n/a
UniProt	P18621	n/a
RefSeq (mRNA)	NM_001199345 NM_000985 NM_001035006 NM_001199340 NM_001199341 NM_001199342 NM_001199343 NM_001199344	n/a
RefSeq (protein)	NP_000976 NP_001030178 NP_001186269 NP_001186270 NP_001186271 NP_001186272 NP_001186273 NP_001186274 NP_001356484 NP_001356485 NP_001356486 NP_001356487 NP_001356489 NP_001356490 NP_001356491 NP_001356492	n/a
Location (UCSC)	Chr 18: 49.49 – 49.49 Mb	n/a
PubMed search	[2]	n/a
Wikidata
View/Edit Human

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L22P family of ribosomal proteins. It is located in the cytoplasm. This gene has been referred to as RPL23 because the encoded protein shares amino acid identity with ribosomal protein L23 from Halobacterium marismortui; however, its official symbol is RPL17. Two alternative splice variants have been observed, each encoding the same protein. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.[5]