BDPC

BDPC
Clinical data
ATC code
  • None
Identifiers
CAS Number
PubChem CID
ChemSpider
Chemical and physical data
Formula C22H28BrNO
Molar mass 402.37 g/mol
3D model (JSmol)
Melting point 208 to 210 °C (406 to 410 °F)
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BDPC (systematic name 4-(4-bromophenyl)-4-(dimethylamino)-1-(2-phenylethyl)cyclohexanol; also known as bromadol) is a potent narcotic analgesic with a distinctive arylcyclohexylamine chemical structure. It was developed by Daniel Lednicer at Upjohn in the 1970s.[1] Initial studies estimated that it was around 10,000 times the strength of morphine in animal models.[2] However, later studies assigned a value of 504 times the potency of morphine for the more active trans-isomer.[3] To date, it is unknown if this drug has been used by humans, however, it was seized along with three kilograms of acetylfentanyl in an April 25, 2013 police action in Montreal, Canada.[4]

See also

References

  1. ↑ U.S. Patent 4,366,172 - 4-Amino-cyclohexanols, their pharmaceutical compositions and methods of use
  2. ↑ Lednicer, D.; Vonvoigtlander, P. F. (1979). "4-(p-Bromophenyl)-4-(dimethylamino)-1-phenethylcyclohexanol, an extremely potent representative of a new analgesic series". Journal of Medicinal Chemistry. 22 (10): 1157–1158. doi:10.1021/jm00196a001. PMID 513062.
  3. ↑ Liu, Z. H.; Jin, W. Q.; Dai, Q. Y.; Chen, X. J.; Zhang, H. P.; Chi, Z. Q. (2003). "Opioid activity of C8813, a novel and potent opioid analgesic". Life Sciences. 73 (2): 233–241. doi:10.1016/S0024-3205(03)00263-7. PMID 12738037.
  4. ↑ "Extremely potent painkiller hits Montreal black market". CBC News. May 13, 2013.
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