KCNV1

KCNV1
Identifiers
Aliases	KCNV1, HNKA, KCNB3, KV2.3, KV8.1, potassium voltage-gated channel modifier subfamily V member 1
External IDs	OMIM: 608164 MGI: 1914748 HomoloGene: 22811 GeneCards: KCNV1
Gene location (Human)
Chr.	Chromosome 8 (human)[1]
End	109,975,771 bp[1]
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)[2]
End	45,114,920 bp[2]
Gene ontology
Molecular function	• ion channel inhibitor activity; • potassium channel regulator activity; • ion channel activity; • voltage-gated ion channel activity; • potassium channel activity; • voltage-gated potassium channel activity;
Cellular component	• cell membrane; • membrane; • voltage-gated potassium channel complex; • integral component of membrane; • integral component of plasma membrane;
Biological process	• ion transport; • transmembrane transport; • potassium ion transport; • protein homooligomerization; • regulation of ion transmembrane transport; • potassium ion transmembrane transport;
	Sources:Amigo / QuickGO
Orthologs
	27012
	67498
	ENSG00000164794
	ENSMUSG00000022342
	Q6PIU1
	Q8BZN2
	NM_014379
	NM_026200
	NP_055194
	NP_080476
	Wikidata
View/Edit Human	View/Edit Mouse

Potassium voltage-gated channel subfamily V member 1 is a protein that in humans is encoded by the KCNV1 gene.[5][6] The protein encoded by this gene is a voltage-gated potassium channel subunit.[5][6]

Common variations in the KCNV1 gene have been associated with schizophrenia.[7]

References

GRCh38: Ensembl release 89: ENSG00000164794 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000022342 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Hugnot JP, Salinas M, Lesage F, Guillemare E, de Weille J, Heurteaux C, Mattei MG, Lazdunski M (Aug 1996). "Kv8.1, a new neuronal potassium channel subunit with specific inhibitory properties towards Shab and Shaw channels". EMBO J. 15 (13): 3322–31. doi:10.1002/j.1460-2075.1996.tb00697.x. PMC 451895. PMID 8670833.
Gutman GA, Chandy KG, Grissmer S, Lazdunski M, McKinnon D, Pardo LA, Robertson GA, Rudy B, Sanguinetti MC, Stuhmer W, Wang X (Dec 2005). "International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels". Pharmacol Rev. 57 (4): 473–508. doi:10.1124/pr.57.4.10. PMID 16382104.
Schizophrenia Working Group of the Psychiatric Genomics Consortium (2014-07-24). "Biological insights from 108 schizophrenia-associated genetic loci". Nature. 511 (7510): 421–427. doi:10.1038/nature13595. ISSN 1476-4687. PMC 4112379. PMID 25056061.

Kv8.1+Potassium+Channel at the US National Library of Medicine Medical Subject Headings (MeSH)
KCNV1+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

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