MYO1B

MYO1B
Identifiers
Aliases	MYO1B, myr1, myosin IB, MMIa, MMI-alpha, MYH-1c
External IDs	OMIM: 606537 MGI: 107752 HomoloGene: 7856 GeneCards: MYO1B
Gene location (Human)
Chr.	Chromosome 2 (human)[1]
End	191,425,389 bp[1]
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)[2]
End	51,916,071 bp[2]
Gene ontology
Molecular function	• nucleotide binding; • actin-dependent ATPase activity; • calmodulin binding; • microfilament motor activity; • actin binding; • phosphatidylinositol-4,5-bisphosphate binding; • cellular motor activity; • ATP binding; • phosphatidylinositol-3,4,5-trisphosphate binding; • actin filament binding; • cadherin binding;
Cellular component	• cytoplasm; • trans-Golgi network membrane; • filopodium; • early endosome; • brush border; • actin filament; • perinuclear region of cytoplasm; • endosome membrane; • extracellular exosome; • cell periphery; • myosin complex; • cell membrane; • apical part of cell;
Biological process	• actin filament organization; • actin filament-based movement; • actin filament bundle assembly; • post-Golgi vesicle-mediated transport;
	Sources:Amigo / QuickGO
Orthologs
	4430
	17912
	ENSG00000128641
	ENSMUSG00000018417
	O43795
	P46735
	NM_001130158; NM_001161819; NM_012223; NM_001330237; NM_001330238
	NM_001161817; NM_001290982; NM_010863
	NP_001123630; NP_001155291; NP_001317166; NP_001317167; NP_036355
	NP_001155289; NP_001277911; NP_034993
	Wikidata
View/Edit Human	View/Edit Mouse

Myosin-Ib is a protein that in humans is encoded by the MYO1B gene.[5][6][7]

References

GRCh38: Ensembl release 89: ENSG00000128641 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000018417 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Bement WM, Hasson T, Wirth JA, Cheney RE, Mooseker MS (Aug 1994). "Identification and overlapping expression of multiple unconventional myosin genes in vertebrate cell types". Proc Natl Acad Sci U S A. 91 (14): 6549–53. doi:10.1073/pnas.91.14.6549. PMC 44240. PMID 8022818.
Ruppert C, Kroschewski R, Bahler M (Apr 1993). "Identification, characterization and cloning of myr 1, a mammalian myosin-I". J Cell Biol. 120 (6): 1393–403. doi:10.1083/jcb.120.6.1393. PMC 2119751. PMID 8449985.
"Entrez Gene: MYO1B myosin IB".

Ruppert C, Godel J, Müller RT, et al. (1997). "Localization of the rat myosin I molecules myr 1 and myr 2 and in vivo targeting of their tail domains". J. Cell Sci. 108 (12): 3775–86. PMID 8719884.
Tang N, Ostap EM (2001). "Motor domain-dependent localization of myo1b (myr-1)". Curr. Biol. 11 (14): 1131–5. doi:10.1016/S0960-9822(01)00320-7. PMID 11509238.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Dumont RA, Zhao YD, Holt JR, et al. (2003). "Myosin-I isozymes in neonatal rodent auditory and vestibular epithelia". J. Assoc. Res. Otolaryngol. 3 (4): 375–89. doi:10.1007/s101620020049. PMC 3202438. PMID 12486594.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Salas-Cortes L, Ye F, Tenza D, et al. (2006). "Myosin Ib modulates the morphology and the protein transport within multi-vesicular sorting endosomes". J. Cell Sci. 118 (Pt 20): 4823–32. doi:10.1242/jcs.02607. PMID 16219689.
Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein–protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.

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[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000128641 - Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000018417 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8022818-5] Bement WM, Hasson T, Wirth JA, Cheney RE, Mooseker MS (Aug 1994). "Identification and overlapping expression of multiple unconventional myosin genes in vertebrate cell types". Proc Natl Acad Sci U S A. 91 (14): 6549–53. doi:10.1073/pnas.91.14.6549. PMC 44240. PMID 8022818.

[pmid8449985-6] Ruppert C, Kroschewski R, Bahler M (Apr 1993). "Identification, characterization and cloning of myr 1, a mammalian myosin-I". J Cell Biol. 120 (6): 1393–403. doi:10.1083/jcb.120.6.1393. PMC 2119751. PMID 8449985.

[entrez-7] "Entrez Gene: MYO1B myosin IB".

MYO1B

References

Further reading