DYNC1LI1

DYNC1LI1
Identifiers
Aliases	DYNC1LI1, DNCLI1, LIC1, dynein cytoplasmic 1 light intermediate chain 1, DLC-A
External IDs	OMIM: 615890 MGI: 2135610 HomoloGene: 9403 GeneCards: DYNC1LI1
Gene location (Human)
Chr.	Chromosome 3 (human)[1]
End	32,570,858 bp[1]
RNA expression pattern
	More reference expression data
Gene ontology
Molecular function	• microtubule motor activity; • nucleotide binding; • GDP binding; • dynein heavy chain binding; • GTP binding; • GO:0001948 protein binding; • cellular motor activity; • ATP binding; • RNA binding;
Cellular component	• condensed chromosome kinetochore; • centrosome; • spindle pole; • membrane; • chromosome; • cytoplasmic dynein complex; • dynein complex; • microtubule; • chromosome, centromeric region; • cytoskeleton; • kinetochore; • cytoplasm; • cytosol; • cell membrane; • secretory granule membrane; • ficolin-1-rich granule membrane;
Biological process	• positive regulation of mitotic cell cycle spindle assembly checkpoint; • cell division; • cell cycle; • viral process; • microtubule cytoskeleton organization; • ER to Golgi vesicle-mediated transport; • microtubule-based movement; • antigen processing and presentation of exogenous peptide antigen via MHC class II; • neutrophil degranulation; • sister chromatid cohesion; • transport;
	Sources:Amigo / QuickGO
Orthologs
	51143
	235661
	ENSG00000144635
	n/a
	Q9Y6G9
	Q8R1Q8
	NM_016141; NM_001329135
	NM_146229
	NP_001316064; NP_057225
	NP_666341
	Wikidata
View/Edit Human	View/Edit Mouse

Cytoplasmic dynein 1 light intermediate chain 1 is a protein that in humans is encoded by the DYNC1LI1 gene.[4][5]

References

GRCh38: Ensembl release 89: ENSG00000144635 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Pfister KK, Fisher EM, Gibbons IR, Hays TS, Holzbaur EL, McIntosh JR, Porter ME, Schroer TA, Vaughan KT, Witman GB, King SM, Vallee RB (Nov 2005). "Cytoplasmic dynein nomenclature". J Cell Biol. 171 (3): 411–3. doi:10.1083/jcb.200508078. PMC 2171247. PMID 16260502.
"Entrez Gene: DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1".

Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Tynan SH, Purohit A, Doxsey SJ, Vallee RB (2000). "Light intermediate chain 1 defines a functional subfraction of cytoplasmic dynein which binds to pericentrin". J. Biol. Chem. 275 (42): 32763–8. doi:10.1074/jbc.M001536200. PMID 10893222.
Bielli A, Thörnqvist PO, Hendrick AG, et al. (2001). "The small GTPase Rab4A interacts with the central region of cytoplasmic dynein light intermediate chain-1". Biochem. Biophys. Res. Commun. 281 (5): 1141–53. doi:10.1006/bbrc.2001.4468. PMID 11243854.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
Ballif BA, Villén J, Beausoleil SA, et al. (2005). "Phosphoproteomic analysis of the developing mouse brain". Mol. Cell. Proteomics. 3 (11): 1093–101. doi:10.1074/mcp.M400085-MCP200. PMID 15345747.
Nousiainen M, Silljé HH, Sauer G, et al. (2006). "Phosphoproteome analysis of the human mitotic spindle". Proc. Natl. Acad. Sci. U.S.A. 103 (14): 5391–6. doi:10.1073/pnas.0507066103. PMC 1459365. PMID 16565220.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.

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[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000144635 - Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[3] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid16260502-4] Pfister KK, Fisher EM, Gibbons IR, Hays TS, Holzbaur EL, McIntosh JR, Porter ME, Schroer TA, Vaughan KT, Witman GB, King SM, Vallee RB (Nov 2005). "Cytoplasmic dynein nomenclature". J Cell Biol. 171 (3): 411–3. doi:10.1083/jcb.200508078. PMC 2171247. PMID 16260502.

[entrez-5] "Entrez Gene: DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1".

DYNC1LI1

References

Further reading