MYO1E

MYO1E
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2XMF
Identifiers
Aliases	MYO1E, FSGS6, HuncM-IC, MYO1C, myosin IE
External IDs	OMIM: 601479 MGI: 106621 HomoloGene: 55864 GeneCards: MYO1E
Gene location (Human)
Chr.	Chromosome 15 (human)[1]
End	59,372,871 bp[1]
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)[2]
End	70,399,766 bp[2]
RNA expression pattern
	More reference expression data
Gene ontology
Molecular function	• nucleotide binding; • calmodulin binding; • actin filament binding; • microfilament motor activity; • GO:0001948 protein binding; • phosphatidylinositol binding; • actin binding; • cellular motor activity; • ATP binding; • lipid binding;
Cellular component	• cytoplasm; • intercellular junction; • clathrin-coated endocytic vesicle; • adherens junction; • cell junction; • brush border; • actin cytoskeleton; • extracellular exosome; • cytoskeleton; • cytoplasmic vesicle; • clathrin-coated vesicle; • myosin complex;
Biological process	• haematopoiesis; • endocytosis; • glomerular visceral epithelial cell development; • glomerular basement membrane development; • kidney development; • post-embryonic hemopoiesis; • in utero embryonic development; • actin filament-based movement; • vasculogenesis; • nitrogen compound metabolic process; • glomerular filtration; • platelet-derived growth factor receptor signaling pathway; • metabolism;
	Sources:Amigo / QuickGO
Orthologs
	4643
	71602
	ENSG00000157483
	ENSMUSG00000032220
	Q12965
	E9Q634
	NM_004998
	NM_181072
	NP_004989
	NP_851417
	Wikidata
View/Edit Human	View/Edit Mouse

Myosin-Ie (Myo1e) is a protein that in humans is encoded by the MYO1E gene.[5][6]

Myosin-Ie is a long tailed myosin. It contains an N-terminal motor domain, an IQ motif, a TH1 domain containing a plecstrin homology (PH) domain, a proline rich TH2 domain, and an SH3 domain. [7]

References

GRCh38: Ensembl release 89: ENSG00000157483 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000032220 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Hasson T, Skowron JF, Gilbert DJ, Avraham KB, Perry WL, Bement WM, et al. (September 1996). "Mapping of unconventional myosins in mouse and human". Genomics. 36 (3): 431–9. doi:10.1006/geno.1996.0488. PMID 8884266.
"Entrez Gene: MYO1E myosin IE".
McConnell RE, Tyska MJ (July 2010). "Leveraging the membrane - cytoskeleton interface with myosin-1". Trends in Cell Biology. 20 (7): 418–26. doi:10.1016/j.tcb.2010.04.004. PMC 2897960. PMID 20471271.

External links

Overview of all the structural information available in the PDB for UniProt: E9Q634 (Mouse Unconventional myosin-Ie) at the PDBe-KB.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000157483 - Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000032220 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8884266-5] Hasson T, Skowron JF, Gilbert DJ, Avraham KB, Perry WL, Bement WM, et al. (September 1996). "Mapping of unconventional myosins in mouse and human". Genomics. 36 (3): 431–9. doi:10.1006/geno.1996.0488. PMID 8884266.

[entrez-6] "Entrez Gene: MYO1E myosin IE".

[7] McConnell RE, Tyska MJ (July 2010). "Leveraging the membrane - cytoskeleton interface with myosin-1". Trends in Cell Biology. 20 (7): 418–26. doi:10.1016/j.tcb.2010.04.004. PMC 2897960. PMID 20471271.

MYO1E

References

Further reading

External links