Uridine diphosphate

Uridine diphosphate
Names
	IUPAC name Uridine 5'-(trihydrogen diphosphate)
Identifiers
CAS Number	58-98-0 ;
ChEMBL	ChEMBL130266 ;
ChemSpider	19952429 ;
ECHA InfoCard	100.000.372
IUPHAR/BPS	1749;
MeSH	Uridine+diphosphate
PubChem CID	1158;
	InChI InChI=1S/C9H12N2O6.2H3O4P/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16;21-5(2,3)4/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16);2(H3,1,2,3,4)/t4-,6-,7-,8-;;/m1../s1 Key: PMPFLUWUGZHTOK-WFIJOQBCSA-N ;
Properties
Chemical formula	C9H14N2O12P2
Molar mass	404.161
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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	Infobox references

Uridine diphosphate, abbreviated UDP, is a nucleotide diphosphate. It is an ester of pyrophosphoric acid with the nucleoside uridine. UDP consists of the pyrophosphate group, the pentose sugar ribose, and the nucleobase uracil.

UDP is an important factor in glycogenesis. Before glucose can be stored as glycogen in the liver and muscles, the enzyme UDP-glucose pyrophosphorylase forms a UDP-glucose unit by combining glucose 1-phosphate with uridine triphosphate, cleaving a pyrophosphate ion in the process. Then, the enzyme glycogen synthase combines UDP-glucose units to form a glycogen chain. The UDP molecule is cleaved from the glucose ring during this process and can be reused by UDP-glucose pyrophosphorylase.^[1]^[2]

References

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