Small nucleolar RNA psi18S-1377
| Small nucleolar RNA psi18S-1377 | |
|---|---|
 Predicted secondary structure and sequence conservation of snopsi18S-1377 | |
| Identifiers | |
| Symbol | snopsi18S-1377 |
| Rfam | RF00543 |
| Other data | |
| RNA type | Gene; snRNA; snoRNA; HACA-box |
| Domain(s) | Eukaryota |
| GO | 0006396 0005730 |
| SO | 0000594 |
| PDB structures | PDBe |
Small nucleolar RNA psi18S-1377 (also known as snoRNA psi28S-1377) is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a 'guide RNA'.
This Drosophila-specific snoRNA is a member of the H/ACA box class of snoRNA and is predicted to be responsible for guiding the modification of uridines 1377 and 1279 to pseudouridine in Drosophila 18S rRNA.[1]
References
- ↑ Kiss, Arnold M.; Jády, Beáta E.; Bertrand, Edouard; Kiss, Tamás (2004). "Human Box H/ACA Pseudouridylation Guide RNA Machinery". Molecular and Cellular Biology. 24 (13): 5797–5807. doi:10.1128/MCB.24.13.5797-5807.2004. PMC 480876. PMID 15199136.
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