Small nucleolar RNA SNORA17

Small nucleolar RNA SNORA17
Identifiers
Symbol SNORA17
Alt. Symbols snoACA17
Rfam RF00560
Other data
RNA type Gene; snRNA; snoRNA; HACA-box
Domain(s) Eukaryota
GO 0006396 0005730
SO 0000594
PDB structures PDBe

In molecular biology, SNORA17 (also known as ACA17) is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines.[1] Specifically, it is predicted to guide pseudouridylation of the 28S rRNA at positions U4659 and U4598. It shares the same host gene together with ACA43.

There are many closely related sequences that do not appear to have conserved H and ACA boxes, and may be pseudogenes.

References

  1. ↑ Kiss, Arnold M.; Jády, Beáta E.; Bertrand, Edouard; Kiss, Tamás (2004). "Human Box H/ACA Pseudouridylation Guide RNA Machinery". Molecular and Cellular Biology. 24 (13): 5797–5807. doi:10.1128/MCB.24.13.5797-5807.2004. PMC 480876. PMID 15199136.

Further reading

  • Ofengand, J; Bakin A (1997). "Mapping to nucleotide resolution of pseudouridine residues in large subunit ribosomal RNAs from representative eukaryotes, prokaryotes, archaebacteria, mitochondria and chloroplasts". J Mol Biol. 266 (2): 246&ndash, 268. doi:10.1006/jmbi.1996.0737. PMID 9047361.


This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.